Cyclometalated iridium(III)-guanidinium complexes as mitochondria-targeted anticancer agents.

Song, Xing-Dong; Kong, Xia; He, Shu-Fen; Chen, Jia-Xi; Sun, Jing; Chen, Bing-Bing; Zhao, Jin-Wu; Mao, Zong-Wan

Song, Xing-Dong; Kong, Xia; He, Shu-Fen; Chen, Jia-Xi; Sun, Jing; Chen, Bing-Bing; Zhao, Jin-Wu; Mao, Zong-Wan.

Affiliation

Song XD; School of Pharmacy, Guangdong Medical University, Dongguan, 523808, China.
Kong X; School of Basic Medicine, Guangdong Medical University, Dongguan, 523808, China.
He SF; School of Pharmacy, Guangdong Medical University, Dongguan, 523808, China.
Chen JX; School of Pharmacy, Guangdong Medical University, Dongguan, 523808, China.
Sun J; School of Pharmacy, Guangdong Medical University, Dongguan, 523808, China. Electronic address: sunjing03@foxmail.com.
Chen BB; School of Pharmacy, Guangdong Medical University, Dongguan, 523808, China.
Zhao JW; School of Pharmacy, Guangdong Medical University, Dongguan, 523808, China.
Mao ZW; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou, 510275, China. Electronic address: cesmzw@mail.sysu.edu.cn.

Eur J Med Chem ; 138: 246-254, 2017 Sep 29.

Article de En | MEDLINE | ID: mdl-28668477

Sujet(s)
Mots clés

Apoptosis; Cytotoxicity; Guanidinium; Ir(III) complex; Mitochondria

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Composés organométalliques / Guanidine / Iridium / Mitochondries / Antinéoplasiques Limites: Humans Langue: En Journal: Eur J Med Chem Année: 2017 Type de document: Article Pays d'affiliation: Chine Pays de publication: France

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