Amygdala Volume Differences in Autism Spectrum Disorder Are Related to Anxiety.
J Autism Dev Disord
; 47(12): 3682-3691, 2017 Dec.
Article
de En
| MEDLINE
| ID: mdl-28689329
ABSTRACT
Recent studies suggest that longstanding findings of abnormal amygdala morphology in ASD may be related to symptoms of anxiety. To test this hypothesis, fifty-three children with ASD (mean age = 11.9) underwent structural MRI and were divided into subgroups to compare those with at least one anxiety disorder diagnosis (n = 29) to those without (n = 24) and to a typically developing control group (TDC; n = 37). Groups were matched on age and intellectual level. The ASD and anxiety group showed decreased right amygdala volume (controlled for total brain volume) relative to ASD without anxiety (p = .04) and TDCs (p = .068). Results suggest that youth with ASD and co-occurring anxiety have a distinct neurodevelopmental trajectory.
Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Troubles anxieux
/
Trouble du spectre autistique
/
Amygdale (système limbique)
Limites:
Adolescent
/
Child
/
Female
/
Humans
/
Male
Langue:
En
Journal:
J Autism Dev Disord
Année:
2017
Type de document:
Article
Pays d'affiliation:
États-Unis d'Amérique