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Integrative Genomics Identifies the Molecular Basis of Resistance to Azacitidine Therapy in Myelodysplastic Syndromes.
Unnikrishnan, Ashwin; Papaemmanuil, Elli; Beck, Dominik; Deshpande, Nandan P; Verma, Arjun; Kumari, Ashu; Woll, Petter S; Richards, Laura A; Knezevic, Kathy; Chandrakanthan, Vashe; Thoms, Julie A I; Tursky, Melinda L; Huang, Yizhou; Ali, Zara; Olivier, Jake; Galbraith, Sally; Kulasekararaj, Austin G; Tobiasson, Magnus; Karimi, Mohsen; Pellagatti, Andrea; Wilson, Susan R; Lindeman, Robert; Young, Boris; Ramakrishna, Raj; Arthur, Christopher; Stark, Richard; Crispin, Philip; Curnow, Jennifer; Warburton, Pauline; Roncolato, Fernando; Boultwood, Jacqueline; Lynch, Kevin; Jacobsen, Sten Eirik W; Mufti, Ghulam J; Hellstrom-Lindberg, Eva; Wilkins, Marc R; MacKenzie, Karen L; Wong, Jason W H; Campbell, Peter J; Pimanda, John E.
Affiliation
  • Unnikrishnan A; Adult Cancer Program, Lowy Cancer Research Centre, UNSW, Sydney, NSW 2052, Australia; Prince of Wales Clinical School, UNSW, Sydney, NSW 2052, Australia. Electronic address: ashwin.unnikrishnan@unsw.edu.au.
  • Papaemmanuil E; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Saffron Walden CB10 1SA, UK; Center for Molecular Oncology and Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Beck D; Adult Cancer Program, Lowy Cancer Research Centre, UNSW, Sydney, NSW 2052, Australia; Prince of Wales Clinical School, UNSW, Sydney, NSW 2052, Australia; Centre for Health Technologies and the School of Software, University of Technology, Sydney, NSW 2007, Australia.
  • Deshpande NP; Systems Biology Initiative, School of Biotechnology and Biomolecular Sciences, UNSW, Sydney, NSW 2052, Australia; School of Biotechnology and Biomolecular Sciences, UNSW, Sydney, NSW 2052, Australia.
  • Verma A; Adult Cancer Program, Lowy Cancer Research Centre, UNSW, Sydney, NSW 2052, Australia; Prince of Wales Clinical School, UNSW, Sydney, NSW 2052, Australia; Climate Change Cluster, University of Technology, Sydney, NSW 2007, Australia.
  • Kumari A; Children's Cancer Institute Australia, Sydney, NSW 2052, Australia.
  • Woll PS; Department of Medicine, Center for Hematology and Regenerative Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, 141 86 Stockholm, Sweden; Haematopoietic Stem Cell Biology Laboratory, MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Ox
  • Richards LA; Children's Cancer Institute Australia, Sydney, NSW 2052, Australia.
  • Knezevic K; Adult Cancer Program, Lowy Cancer Research Centre, UNSW, Sydney, NSW 2052, Australia; Prince of Wales Clinical School, UNSW, Sydney, NSW 2052, Australia.
  • Chandrakanthan V; Adult Cancer Program, Lowy Cancer Research Centre, UNSW, Sydney, NSW 2052, Australia; Prince of Wales Clinical School, UNSW, Sydney, NSW 2052, Australia.
  • Thoms JAI; Adult Cancer Program, Lowy Cancer Research Centre, UNSW, Sydney, NSW 2052, Australia; Prince of Wales Clinical School, UNSW, Sydney, NSW 2052, Australia.
  • Tursky ML; Adult Cancer Program, Lowy Cancer Research Centre, UNSW, Sydney, NSW 2052, Australia; Prince of Wales Clinical School, UNSW, Sydney, NSW 2052, Australia; Children's Cancer Institute Australia, Sydney, NSW 2052, Australia; Blood, Stem Cells and Cancer Research, St Vincent's Centre for Applied Medical
  • Huang Y; Adult Cancer Program, Lowy Cancer Research Centre, UNSW, Sydney, NSW 2052, Australia; Prince of Wales Clinical School, UNSW, Sydney, NSW 2052, Australia; Centre for Health Technologies and the School of Software, University of Technology, Sydney, NSW 2007, Australia.
  • Ali Z; Children's Cancer Institute Australia, Sydney, NSW 2052, Australia.
  • Olivier J; School of Mathematics and Statistics, UNSW, Sydney, NSW 2052, Australia.
  • Galbraith S; School of Mathematics and Statistics, UNSW, Sydney, NSW 2052, Australia.
  • Kulasekararaj AG; Department of Haematological Medicine, King's College London School of Medicine, London WC2R 2LS, UK.
  • Tobiasson M; Department of Medicine, Center for Hematology and Regenerative Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, 141 86 Stockholm, Sweden.
  • Karimi M; Department of Medicine, Center for Hematology and Regenerative Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, 141 86 Stockholm, Sweden.
  • Pellagatti A; Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DU, United Kingdom.
  • Wilson SR; School of Mathematics and Statistics, UNSW, Sydney, NSW 2052, Australia; Mathematical Sciences Institute, ANU, Canberra, ACT 0200, Australia.
  • Lindeman R; Haematology Department, South Eastern Area Laboratory Services, Prince of Wales Hospital, Randwick, NSW 2031, Australia.
  • Young B; Haematology Department, South Eastern Area Laboratory Services, Prince of Wales Hospital, Randwick, NSW 2031, Australia.
  • Ramakrishna R; Southern Sydney Haematology, Kogarah, NSW 2217, Australia.
  • Arthur C; Royal North Shore Hospital, St Leonards, NSW 2065, Australia.
  • Stark R; North Coast Cancer Institute, Port Macquarie, NSW 2444, Australia.
  • Crispin P; Canberra Hospital, Canberra, ACT 2605, Australia.
  • Curnow J; Concord Repatriation General Hospital, Concord, NSW 2139, Australia.
  • Warburton P; Wollongong Hospital, Wollongong, NSW 2521, Australia.
  • Roncolato F; St George Hospital, Kogarah, NSW 2217, Australia.
  • Boultwood J; Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DU, United Kingdom.
  • Lynch K; Celgene International, 2017 Boudry, Switzerland.
  • Jacobsen SEW; Department of Medicine, Center for Hematology and Regenerative Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, 141 86 Stockholm, Sweden; Haematopoietic Stem Cell Biology Laboratory, MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Ox
  • Mufti GJ; Department of Haematological Medicine, King's College London School of Medicine, London WC2R 2LS, UK.
  • Hellstrom-Lindberg E; Department of Medicine, Center for Hematology and Regenerative Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, 141 86 Stockholm, Sweden.
  • Wilkins MR; Systems Biology Initiative, School of Biotechnology and Biomolecular Sciences, UNSW, Sydney, NSW 2052, Australia; School of Biotechnology and Biomolecular Sciences, UNSW, Sydney, NSW 2052, Australia; Ramaciotti Centre for Gene Function Analysis, UNSW, Sydney, NSW 2052, Australia.
  • MacKenzie KL; Children's Cancer Institute Australia, Sydney, NSW 2052, Australia.
  • Wong JWH; Adult Cancer Program, Lowy Cancer Research Centre, UNSW, Sydney, NSW 2052, Australia; Prince of Wales Clinical School, UNSW, Sydney, NSW 2052, Australia.
  • Campbell PJ; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Saffron Walden CB10 1SA, UK. Electronic address: pc8@sanger.ac.uk.
  • Pimanda JE; Adult Cancer Program, Lowy Cancer Research Centre, UNSW, Sydney, NSW 2052, Australia; Prince of Wales Clinical School, UNSW, Sydney, NSW 2052, Australia; Haematology Department, South Eastern Area Laboratory Services, Prince of Wales Hospital, Randwick, NSW 2031, Australia. Electronic address: jpima
Cell Rep ; 20(3): 572-585, 2017 07 18.
Article de En | MEDLINE | ID: mdl-28723562
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Azacitidine / Syndromes myélodysplasiques / Résistance aux substances / Génomique Limites: Aged / Aged80 / Female / Humans / Middle aged Langue: En Journal: Cell Rep Année: 2017 Type de document: Article Pays de publication: États-Unis d'Amérique
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Azacitidine / Syndromes myélodysplasiques / Résistance aux substances / Génomique Limites: Aged / Aged80 / Female / Humans / Middle aged Langue: En Journal: Cell Rep Année: 2017 Type de document: Article Pays de publication: États-Unis d'Amérique