Data on MyoD reduction by autophagy in C2C12 cells.
Data Brief
; 13: 650-654, 2017 Aug.
Article
de En
| MEDLINE
| ID: mdl-28725668
ABSTRACT
Autophagy is a highly regulated physiologic mechanism in which cells maintain homeostasis by degrading excessive or unnecessary proteins and damaged or aged organelles through the lysosomal machinery (Yorimitsu and Klionsky, 2005) [1]. MyoD is basic helix-loop-helix (bHLH) transcription factors that regulate myoblast proliferation and myogenic differentiation. MyoD is expressed in adult skeletal muscle (Megeney et al., 1996) [2] and adult fibers (Brack et al., 2005) [3]. MyoD is mainly degraded by the ubiquitin-proteasome system (Floyd et al., 2001) [4] and partly by autophagy (Kim et al., 2012) [5]. Data showed that autophagy decreased MyoD protein in C2C12 cells by Western blotting analysis.
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1
Collection:
01-internacional
Base de données:
MEDLINE
Langue:
En
Journal:
Data Brief
Année:
2017
Type de document:
Article