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Hypermethylation of MIR21 in CD4+ T cells from patients with relapsing-remitting multiple sclerosis associates with lower miRNA-21 levels and concomitant up-regulation of its target genes.
Ruhrmann, Sabrina; Ewing, Ewoud; Piket, Eliane; Kular, Lara; Cetrulo Lorenzi, Julio Cesar; Fernandes, Sunjay Jude; Morikawa, Hiromasa; Aeinehband, Shahin; Sayols-Baixeras, Sergi; Aslibekyan, Stella; Absher, Devin M; Arnett, Donna K; Tegner, Jesper; Gomez-Cabrero, David; Piehl, Fredrik; Jagodic, Maja.
Affiliation
  • Ruhrmann S; Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.
  • Ewing E; Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.
  • Piket E; Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.
  • Kular L; Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.
  • Cetrulo Lorenzi JC; Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden/ Department of Genetics, Medical School of Ribeirão Preto, São Paulo University, Ribeirão Preto, Brazil.
  • Fernandes SJ; Unit of Computational Medicine, Department of Medicine, Solna, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden/ Science for Life Laboratory, Stockholm, Sweden.
  • Morikawa H; Unit of Computational Medicine, Department of Medicine, Solna, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden/ Science for Life Laboratory, Stockholm, Sweden.
  • Aeinehband S; Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.
  • Sayols-Baixeras S; Cardiovascular Epidemiology and Genetics Group, Institut Hospital del Mar d'Investigacions Mediques (IMIM), Barcelona, Spain/ Universitat Pompeu Fabra (UPF), Barcelona, Spain.
  • Aslibekyan S; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA.
  • Absher DM; HudsonAlpha Institute for Biotechnology, Huntsville, AL, USA.
  • Arnett DK; College of Public Health, University of Kentucky, Lexington, KY, USA.
  • Tegner J; Unit of Computational Medicine, Department of Medicine, Solna, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden/ Science for Life Laboratory, Stockholm, Sweden/ Biological and Environmental Sciences and Engineering Division, Computer, Electrical and Mathematical Sciences and E
  • Gomez-Cabrero D; Unit of Computational Medicine, Department of Medicine, Solna, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden/ Mucosal & Salivary Biology Division, Dental Institute, King's College London, London, UK.
  • Piehl F; Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.
  • Jagodic M; Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.
Mult Scler ; 24(10): 1288-1300, 2018 09.
Article de En | MEDLINE | ID: mdl-28766461
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Lymphocytes T CD4/ / Régulation de l'expression des gènes / Sclérose en plaques chronique progressive / Sclérose en plaques récurrente-rémittente / MicroARN Type d'étude: Prognostic_studies / Risk_factors_studies Limites: Adult / Female / Humans / Male / Middle aged Langue: En Journal: Mult Scler Sujet du journal: NEUROLOGIA Année: 2018 Type de document: Article Pays d'affiliation: Suède Pays de publication: Royaume-Uni
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Lymphocytes T CD4/ / Régulation de l'expression des gènes / Sclérose en plaques chronique progressive / Sclérose en plaques récurrente-rémittente / MicroARN Type d'étude: Prognostic_studies / Risk_factors_studies Limites: Adult / Female / Humans / Male / Middle aged Langue: En Journal: Mult Scler Sujet du journal: NEUROLOGIA Année: 2018 Type de document: Article Pays d'affiliation: Suède Pays de publication: Royaume-Uni