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Takinib, a Selective TAK1 Inhibitor, Broadens the Therapeutic Efficacy of TNF-α Inhibition for Cancer and Autoimmune Disease.
Totzke, Juliane; Gurbani, Deepak; Raphemot, Rene; Hughes, Philip F; Bodoor, Khaldon; Carlson, David A; Loiselle, David R; Bera, Asim K; Eibschutz, Liesl S; Perkins, Marisha M; Eubanks, Amber L; Campbell, Phillip L; Fox, David A; Westover, Kenneth D; Haystead, Timothy A J; Derbyshire, Emily R.
Affiliation
  • Totzke J; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC 27710, USA.
  • Gurbani D; Departments of Biochemistry and Radiation Oncology, University of Texas, Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA.
  • Raphemot R; Department of Chemistry, Duke University, Durham, NC 27710, USA.
  • Hughes PF; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC 27710, USA.
  • Bodoor K; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC 27710, USA; Department of Applied Biology, Jordan University of Science and Technology, PO Box 3030, Irbid 22110, Jordan.
  • Carlson DA; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC 27710, USA.
  • Loiselle DR; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC 27710, USA.
  • Bera AK; Departments of Biochemistry and Radiation Oncology, University of Texas, Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA.
  • Eibschutz LS; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC 27710, USA.
  • Perkins MM; Department of Chemistry, Duke University, Durham, NC 27710, USA.
  • Eubanks AL; Department of Chemistry, Duke University, Durham, NC 27710, USA.
  • Campbell PL; University of Michigan, Division of Rheumatology and Clinical Autoimmunity Center of Excellence, Ann Arbor, MI 48109, USA.
  • Fox DA; University of Michigan, Division of Rheumatology and Clinical Autoimmunity Center of Excellence, Ann Arbor, MI 48109, USA.
  • Westover KD; Departments of Biochemistry and Radiation Oncology, University of Texas, Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA. Electronic address: kenneth.westover@utsouthwestern.edu.
  • Haystead TAJ; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC 27710, USA. Electronic address: timothy.haystead@duke.edu.
  • Derbyshire ER; Department of Chemistry, Duke University, Durham, NC 27710, USA. Electronic address: emily.derbyshire@duke.edu.
Cell Chem Biol ; 24(8): 1029-1039.e7, 2017 Aug 17.
Article de En | MEDLINE | ID: mdl-28820959

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Benzamides / Benzimidazoles / Facteur de nécrose tumorale alpha / MAP Kinase Kinase Kinases / Inhibiteurs de protéines kinases Type d'étude: Prognostic_studies Limites: Female / Humans Langue: En Journal: Cell Chem Biol Année: 2017 Type de document: Article Pays d'affiliation: États-Unis d'Amérique

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Benzamides / Benzimidazoles / Facteur de nécrose tumorale alpha / MAP Kinase Kinase Kinases / Inhibiteurs de protéines kinases Type d'étude: Prognostic_studies Limites: Female / Humans Langue: En Journal: Cell Chem Biol Année: 2017 Type de document: Article Pays d'affiliation: États-Unis d'Amérique