C-terminal BRE overexpression in 11q23-rearranged and t(8;16) acute myeloid leukemia is caused by intragenic transcription initiation.

Marneth, A E; Prange, K H M; Al Hinai, A S A; Bergevoet, S M; Tesi, N; Janssen-Megens, E M; Kim, B; Sharifi, N; Yaspo, M L; Kuster, J; Sanders, M A; Stoetman, E C G; Knijnenburg, J; Arentsen-Peters, T C J M; Zwaan, C M; Stunnenberg, H G; van den Heuvel-Eibrink, M M; Haferlach, T; Fornerod, M; Jansen, J H; Valk, P J M; van der Reijden, B A; Martens, J H A

Marneth, A E; Prange, K H M; Al Hinai, A S A; Bergevoet, S M; Tesi, N; Janssen-Megens, E M; Kim, B; Sharifi, N; Yaspo, M L; Kuster, J; Sanders, M A; Stoetman, E C G; Knijnenburg, J; Arentsen-Peters, T C J M; Zwaan, C M; Stunnenberg, H G; van den Heuvel-Eibrink, M M; Haferlach, T; Fornerod, M; Jansen, J H; Valk, P J M; van der Reijden, B A; Martens, J H A.

Affiliation

Marneth AE; Department of Laboratory Medicine, Laboratory of Hematology, Radboud Institute for Molecular Life Sciences (RIMLS), Radboud University Medical Center, Nijmegen, The Netherlands.
Prange KHM; Department of Molecular Biology, Faculty of Science, RIMLS, Radboud University, Nijmegen, The Netherlands.
Al Hinai ASA; Department of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Bergevoet SM; Department of Laboratory Medicine, Laboratory of Hematology, Radboud Institute for Molecular Life Sciences (RIMLS), Radboud University Medical Center, Nijmegen, The Netherlands.
Tesi N; Department of Molecular Biology, Faculty of Science, RIMLS, Radboud University, Nijmegen, The Netherlands.
Janssen-Megens EM; Department of Molecular Biology, Faculty of Science, RIMLS, Radboud University, Nijmegen, The Netherlands.
Kim B; Department of Molecular Biology, Faculty of Science, RIMLS, Radboud University, Nijmegen, The Netherlands.
Sharifi N; Department of Molecular Biology, Faculty of Science, RIMLS, Radboud University, Nijmegen, The Netherlands.
Yaspo ML; Max Planck Institute for Molecular Genetics, Berlin, Germany.
Kuster J; Department of Molecular Biology, Faculty of Science, RIMLS, Radboud University, Nijmegen, The Netherlands.
Sanders MA; Department of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Stoetman ECG; Department of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Knijnenburg J; Department of Clinical Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands.
Arentsen-Peters TCJM; Pediatric Oncology/Hematology, Erasmus University Medical Center-Sophia Children's Hospital, Rotterdam, The Netherlands.
Zwaan CM; Pediatric Oncology/Hematology, Erasmus University Medical Center-Sophia Children's Hospital, Rotterdam, The Netherlands.
Stunnenberg HG; Department of Molecular Biology, Faculty of Science, RIMLS, Radboud University, Nijmegen, The Netherlands.
van den Heuvel-Eibrink MM; Pediatric Oncology/Hematology, Erasmus University Medical Center-Sophia Children's Hospital, Rotterdam, The Netherlands.
Haferlach T; Princess Maxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Fornerod M; MLL Munich Leukemia Laboratory, Munich, Germany.
Jansen JH; Pediatric Oncology/Hematology, Erasmus University Medical Center-Sophia Children's Hospital, Rotterdam, The Netherlands.
Valk PJM; Department of Laboratory Medicine, Laboratory of Hematology, Radboud Institute for Molecular Life Sciences (RIMLS), Radboud University Medical Center, Nijmegen, The Netherlands.
van der Reijden BA; Department of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Martens JHA; Department of Laboratory Medicine, Laboratory of Hematology, Radboud Institute for Molecular Life Sciences (RIMLS), Radboud University Medical Center, Nijmegen, The Netherlands.

Leukemia ; 32(3): 828-836, 2018 03.

Article de En | MEDLINE | ID: mdl-28871137

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Translocation génétique / Réarrangement des gènes / Leucémie aigüe myéloïde / Activation de la transcription / Motifs et domaines d'intéraction protéique / Protéines de tissu nerveux Limites: Humans Langue: En Journal: Leukemia Sujet du journal: HEMATOLOGIA / NEOPLASIAS Année: 2018 Type de document: Article Pays d'affiliation: Pays-Bas Pays de publication: Royaume-Uni

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