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Generation and CRISPR/Cas9 editing of transformed progenitor B cells as a pseudo-physiological system to study DNA repair gene function in V(D)J recombination.
Lenden Hasse, Hélène; Lescale, Chloé; Bianchi, Joy J; Yu, Wei; Bedora-Faure, Marie; Deriano, Ludovic.
Affiliation
  • Lenden Hasse H; Genome Integrity, Immunity and Cancer Unit, Department of Immunology, Department of Genomes and Genetics, Institut Pasteur, 75015 Paris, France.
  • Lescale C; Genome Integrity, Immunity and Cancer Unit, Department of Immunology, Department of Genomes and Genetics, Institut Pasteur, 75015 Paris, France.
  • Bianchi JJ; Genome Integrity, Immunity and Cancer Unit, Department of Immunology, Department of Genomes and Genetics, Institut Pasteur, 75015 Paris, France; Cellule Pasteur, University of Paris René Descartes, Sorbonne Paris Cité, Paris 75015, France.
  • Yu W; Genome Integrity, Immunity and Cancer Unit, Department of Immunology, Department of Genomes and Genetics, Institut Pasteur, 75015 Paris, France.
  • Bedora-Faure M; Genome Integrity, Immunity and Cancer Unit, Department of Immunology, Department of Genomes and Genetics, Institut Pasteur, 75015 Paris, France.
  • Deriano L; Genome Integrity, Immunity and Cancer Unit, Department of Immunology, Department of Genomes and Genetics, Institut Pasteur, 75015 Paris, France. Electronic address: ludovic.deriano@pasteur.fr.
J Immunol Methods ; 451: 71-77, 2017 12.
Article de En | MEDLINE | ID: mdl-28882611
Sujet(s)
Mots clés

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Cassures double-brin de l'ADN / Précurseurs lymphoïdes B / Réparation de l'ADN par recombinaison / Protéines associées aux CRISPR / Clustered regularly interspaced short palindromic repeats / Systèmes CRISPR-Cas / Édition de gène Type d'étude: Prognostic_studies Limites: Animals Langue: En Journal: J Immunol Methods Année: 2017 Type de document: Article Pays d'affiliation: France

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Cassures double-brin de l'ADN / Précurseurs lymphoïdes B / Réparation de l'ADN par recombinaison / Protéines associées aux CRISPR / Clustered regularly interspaced short palindromic repeats / Systèmes CRISPR-Cas / Édition de gène Type d'étude: Prognostic_studies Limites: Animals Langue: En Journal: J Immunol Methods Année: 2017 Type de document: Article Pays d'affiliation: France