Binding of NAD<sup>+</sup>-Glycohydrolase to Streptolysin O Stabilizes Both Toxins and Promotes Virulence of Group A <i>Streptococcus</i>.

Velarde, Jorge J; O'Seaghdha, Maghnus; Baddal, Buket; Bastiat-Sempe, Benedicte; Wessels, Michael R

Binding of NAD⁺-Glycohydrolase to Streptolysin O Stabilizes Both Toxins and Promotes Virulence of Group A Streptococcus.

Velarde, Jorge J; O'Seaghdha, Maghnus; Baddal, Buket; Bastiat-Sempe, Benedicte; Wessels, Michael R.

Affiliation

Velarde JJ; Division of Infectious Diseases, Boston Children's Hospital, and Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA.
O'Seaghdha M; Division of Infectious Diseases, Boston Children's Hospital, and Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA.
Baddal B; Division of Infectious Diseases, Boston Children's Hospital, and Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA.
Bastiat-Sempe B; Division of Infectious Diseases, Boston Children's Hospital, and Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA.
Wessels MR; Division of Infectious Diseases, Boston Children's Hospital, and Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA Michael.Wessels@childrens.harvard.edu.

mBio ; 8(5)2017 09 12.

Article de En | MEDLINE | ID: mdl-28900022

Sujet(s)
Mots clés

NAD+-glycohydrolase; Streptococcus pyogenes; cholesterol-dependent cytolysin; pore-forming toxins; streptolysin O

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Streptococcus pyogenes / Streptolysines / NAD nucleosidase Type d'étude: Prognostic_studies Limites: Humans Langue: En Journal: MBio Année: 2017 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: États-Unis d'Amérique

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