Mitochondrial toxicity of triclosan on mammalian cells.

Ajao, Charmaine; Andersson, Maria A; Teplova, Vera V; Nagy, Szabolcs; Gahmberg, Carl G; Andersson, Leif C; Hautaniemi, Maria; Kakasi, Balazs; Roivainen, Merja; Salkinoja-Salonen, Mirja

Ajao, Charmaine; Andersson, Maria A; Teplova, Vera V; Nagy, Szabolcs; Gahmberg, Carl G; Andersson, Leif C; Hautaniemi, Maria; Kakasi, Balazs; Roivainen, Merja; Salkinoja-Salonen, Mirja.

Affiliation

Ajao C; Department of Food and Environmental Sciences, Haartman Institute, University of Helsinki, POB 56, FI-00014, Finland.
Andersson MA; Department of Food and Environmental Sciences, Haartman Institute, University of Helsinki, POB 56, FI-00014, Finland.
Teplova VV; Institute of Theoretical and Experimental Biophysics, RAS, Puschino, Moscow Region, Russia.
Nagy S; Department of Animal Science and Animal Husbandry, University of Pannonia, Georgikon Faculty, Deak F. u.,16, H8360 Keszthely, Hungary.
Gahmberg CG; Dept. of Bio- and Environmental Sciences, Haartman Institute, University of Helsinki, FI-00014, Finland.
Andersson LC; Dept. of Pathology, Haartman Institute, University of Helsinki, FI-00014, Finland.
Hautaniemi M; Finnish Food Safety Authority (EVIRA), Research and Laboratory Department, Veterinary Virology Research Unit, Mustialankatu 3, FI 00790 Helsinki, Finland.
Kakasi B; Institute of Environmental Sciences, University of Pannonia, Egyetem u. 10, H-8200 Veszprem, Hungary.
Roivainen M; National Institute for Health and Welfare, Department of Virology, Mannerheimintie 166, 00300 Helsinki, Finland.
Salkinoja-Salonen M; Department of Food and Environmental Sciences, Haartman Institute, University of Helsinki, POB 56, FI-00014, Finland.

Toxicol Rep ; 2: 624-637, 2015.

Article de En | MEDLINE | ID: mdl-28962398

Mots clés

Acidosis; BCF, bioconcentration factor; EC50, concentration that diminishes the respective vitality parameter by ≥50%; Electric transmembrane potential; Glycolysis; HaCaT, a spontaneously immortalized (non-neoplastic) keratinocyte cell line; JC-1, 5,5',6,6'-tetrachloro-1,1',3,3'-tetraethylbenzimidazolyl-carbocyanine iodide; MIC, minimal inhibitory concentration; MIN-6, a murine pancreatic beta cell line; MNA, a murine neuroblastoma cells; Oxidative phosphorylation; PBMC, monocyte-enriched peripheral blood mononuclear cells; PI, propidium iodide; PK-15, a porcine kidney tubular epithelial cell line; PN, pyridine nucleotides; RLM, rat liver mitochondria; Sperm motility; TPP+, tetraphenylphosphonium; Uncoupler; ΔΨ, electric transmembrane potential; ΔΨm, membrane potential of the mitochondrial membrane; ΔΨp, membrane potential of the plasma membrane

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Langue: En Journal: Toxicol Rep Année: 2015 Type de document: Article Pays d'affiliation: Finlande Pays de publication: Irlande

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