First-line pembrolizumab in cisplatin-ineligible patients with locally advanced and unresectable or metastatic urothelial cancer (KEYNOTE-052): a multicentre, single-arm, phase 2 study.

Balar, Arjun V; Castellano, Daniel; O'Donnell, Peter H; Grivas, Petros; Vuky, Jacqueline; Powles, Thomas; Plimack, Elizabeth R; Hahn, Noah M; de Wit, Ronald; Pang, Lei; Savage, Mary J; Perini, Rodolfo F; Keefe, Stephen M; Bajorin, Dean; Bellmunt, Joaquim

Balar, Arjun V; Castellano, Daniel; O'Donnell, Peter H; Grivas, Petros; Vuky, Jacqueline; Powles, Thomas; Plimack, Elizabeth R; Hahn, Noah M; de Wit, Ronald; Pang, Lei; Savage, Mary J; Perini, Rodolfo F; Keefe, Stephen M; Bajorin, Dean; Bellmunt, Joaquim.

Affiliation

Balar AV; Perlmutter Cancer Center, NYU Langone Medical Center, New York, NY, USA. Electronic address: arjun.balar@nyumc.org.
Castellano D; Hospital Universitario 12 de Octubre (CiberOnc), Madrid, Spain.
O'Donnell PH; University of Chicago Medical Center, Chicago, IL, USA.
Grivas P; Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA.
Vuky J; Oregon Health & Science University, Portland, OR, USA.
Powles T; Barts Cancer Institute, Queen Mary University of London, London, UK.
Plimack ER; Fox Chase Cancer Center, Philadelphia, PA, USA.
Hahn NM; Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, USA.
de Wit R; Erasmus MC Cancer Institute, Rotterdam, Netherlands.
Pang L; Merck & Co, Kenilworth, NJ, USA.
Savage MJ; Merck & Co, Kenilworth, NJ, USA.
Perini RF; Merck & Co, Kenilworth, NJ, USA.
Keefe SM; Merck & Co, Kenilworth, NJ, USA.
Bajorin D; Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Bellmunt J; Dana-Farber Cancer Institute, Boston, MA, USA.

Lancet Oncol ; 18(11): 1483-1492, 2017 11.

Article de En | MEDLINE | ID: mdl-28967485

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Carcinome transitionnel / Tumeurs urologiques / Anticorps monoclonaux humanisés Type d'étude: Clinical_trials / Observational_studies / Prognostic_studies / Risk_factors_studies Limites: Aged / Aged80 / Humans / Middle aged Langue: En Journal: Lancet Oncol Sujet du journal: NEOPLASIAS Année: 2017 Type de document: Article

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