Reducing intraocular-pressure spike after intravitreal-bevacizumab injection with ocular decompression using a sterile cotton swab soaked in proparacaine 0.5%: A quasi-experimental study.
Taiwan J Ophthalmol
; 6(2): 75-78, 2016.
Article
de En
| MEDLINE
| ID: mdl-29018715
ABSTRACT
BACKGROUND/PURPOSE:
The study was conducted to determine the effect of preinjection ocular decompression by a cotton swab soaked in local anesthetic on the immediate postinjection rise in intraocular pressure (IOP) after intravitreal bevacizumab (IVB).METHODS:
A nonrandomized, quasi-experimental interventional study was conducted at Al-Shifa Trust Eye Hospital, Pakistan, from August 1, 2013 to July 31, 2014. One hundred (n = 100) patients receiving 0.05-mL IVB injection for the first time were assigned to two preinjection anestheticmethods:
one with ocular decompression using a sterile cotton swab soaked in proparacaine 0.5%, and the other without ocular decompression using proparacaine 0.5% eyedrops. The IOP was recorded in the eye receiving IVB at three time intervals Time 1 (preinjection), Time 2 (immediately after injection), and Time 3 (30 minutes after injection).RESULTS:
There was a significant difference in the mean IOP change (between Time 1 and Time 2) for the group injected with ocular decompression [M = 1.00, standard deviation (SD) = 1.47] and the group injected without ocular decompression (M = 5.00, SD = 2.38; t (68) = 9.761, p < 0.001). There was also a significant difference in the mean IOP change (between Time 1 and Time 3) for the group injected with ocular decompression (M = 0.428, SD = 1.58) and the group injected without ocular decompression (M = 4.318, SD = 3.34; t (58) = 7.111, p < 0.001).CONCLUSION:
Patients receiving IVB injections with ocular-decompression soaking in proparacaine 0.5% experience significantly lower postinjection IOP spike, and that too for a considerably shorter duration as compared to those receiving IVB without ocular decompression.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Langue:
En
Journal:
Taiwan J Ophthalmol
Année:
2016
Type de document:
Article
Pays d'affiliation:
Pakistan
Pays de publication:
IN
/
INDIA
/
ÍNDIA