Effects of 2-amino-9H-pyrido[2,3-b]indole (A&#945;C) metabolic bio-activation on oxidative DNA damage in human hepatoma G2 (HepG2) cells.

Liu, Xianjun; Zhang, Tingting; Li, Xiang; Zhao, Ge; Xie, Fuwei

Effects of 2-amino-9H-pyrido[2,3-b]indole (AαC) metabolic bio-activation on oxidative DNA damage in human hepatoma G2 (HepG2) cells.

Liu, Xianjun; Zhang, Tingting; Li, Xiang; Zhao, Ge; Xie, Fuwei.

Affiliation

Liu X; a Key Laboratory of Tobacco Chemistry , Zhengzhou Tobacco Research Institute of CNTC , Zhengzhou , China.
Zhang T; b Technology Center of Henan Tobacco Industrial Co., Ltd , Zhengzhou , China.
Li X; a Key Laboratory of Tobacco Chemistry , Zhengzhou Tobacco Research Institute of CNTC , Zhengzhou , China.
Zhao G; a Key Laboratory of Tobacco Chemistry , Zhengzhou Tobacco Research Institute of CNTC , Zhengzhou , China.
Xie F; a Key Laboratory of Tobacco Chemistry , Zhengzhou Tobacco Research Institute of CNTC , Zhengzhou , China.

Toxicol Mech Methods ; 28(3): 230-237, 2018 Mar.

Article de En | MEDLINE | ID: mdl-29022416

Sujet(s)
Mots clés

2-amino-9H-pyrido[2,3-b]indole (AαC; CAS: 26148-68-5); HepG2 cells; hydroxylated metabolites; metabolic bio-activation; oxidative DNA damage

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Altération de l'ADN / Carbolines / Cancérogènes environnementaux / Hépatoblastome / Stress oxydatif / Hépatocytes / Tumeurs du foie Limites: Animals / Humans Langue: En Journal: Toxicol Mech Methods Sujet du journal: TOXICOLOGIA Année: 2018 Type de document: Article Pays d'affiliation: Chine

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