Similarities and Differences in Genetics.
Adv Exp Med Biol
; 1010: 59-71, 2017.
Article
de En
| MEDLINE
| ID: mdl-29098668
ABSTRACT
Similar symptomatology manifestations and high co-morbidity in substance and non-substance addictions suggest that there may be a common pathogenesis between them. Associated with impulse control and emotional processing, the monoamine neurotransmitter system genes are suggested to be related to both substance and non-substance addictions, such as dopamine (DA) system, 5-hydroxytryptamine/serotonin (5-HT) system, the endogenous opioid system and so on. Here we reviewed the similarities and differences in genetics between classic substance addiction and common types of non-substance addiction, e.g. pathological gambling, Internet addiction, binge-eating disorder etc. It is necessary to systematically compare genetic mechanisms of non-substance addiction and substance addiction, which could reveal similarities and differences of substance addiction and non-addictive substances essentially, enhance our understanding of addiction theory and improve clinical practice with research results.
Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Encéphale
/
Comportement toxicomaniaque
/
Troubles liés à une substance
/
Protéines de tissu nerveux
Limites:
Animals
/
Humans
Langue:
En
Journal:
Adv Exp Med Biol
Année:
2017
Type de document:
Article
Pays d'affiliation:
Chine