RSPO3 antagonism inhibits growth and tumorigenicity in colorectal tumors harboring common Wnt pathway mutations.

Fischer, Marcus M; Yeung, V Pete; Cattaruzza, Fiore; Hussein, Rajaa; Yen, Wan-Ching; Murriel, Christopher; Evans, James W; O'Young, Gilbert; Brunner, Alayne L; Wang, Min; Cain, Jennifer; Cancilla, Belinda; Kapoun, Ann; Hoey, Timothy

Fischer, Marcus M; Yeung, V Pete; Cattaruzza, Fiore; Hussein, Rajaa; Yen, Wan-Ching; Murriel, Christopher; Evans, James W; O'Young, Gilbert; Brunner, Alayne L; Wang, Min; Cain, Jennifer; Cancilla, Belinda; Kapoun, Ann; Hoey, Timothy.

Affiliation

Fischer MM; OncoMed Pharmaceuticals, Inc. 800 Chesapeake Drive, Redwood City, CA, 94063, USA.
Yeung VP; OncoMed Pharmaceuticals, Inc. 800 Chesapeake Drive, Redwood City, CA, 94063, USA.
Cattaruzza F; OncoMed Pharmaceuticals, Inc. 800 Chesapeake Drive, Redwood City, CA, 94063, USA.
Hussein R; OncoMed Pharmaceuticals, Inc. 800 Chesapeake Drive, Redwood City, CA, 94063, USA.
Yen WC; OncoMed Pharmaceuticals, Inc. 800 Chesapeake Drive, Redwood City, CA, 94063, USA.
Murriel C; OncoMed Pharmaceuticals, Inc. 800 Chesapeake Drive, Redwood City, CA, 94063, USA.
Evans JW; OncoMed Pharmaceuticals, Inc. 800 Chesapeake Drive, Redwood City, CA, 94063, USA.
O'Young G; OncoMed Pharmaceuticals, Inc. 800 Chesapeake Drive, Redwood City, CA, 94063, USA.
Brunner AL; OncoMed Pharmaceuticals, Inc. 800 Chesapeake Drive, Redwood City, CA, 94063, USA.
Wang M; OncoMed Pharmaceuticals, Inc. 800 Chesapeake Drive, Redwood City, CA, 94063, USA.
Cain J; OncoMed Pharmaceuticals, Inc. 800 Chesapeake Drive, Redwood City, CA, 94063, USA.
Cancilla B; OncoMed Pharmaceuticals, Inc. 800 Chesapeake Drive, Redwood City, CA, 94063, USA.
Kapoun A; OncoMed Pharmaceuticals, Inc. 800 Chesapeake Drive, Redwood City, CA, 94063, USA.
Hoey T; OncoMed Pharmaceuticals, Inc. 800 Chesapeake Drive, Redwood City, CA, 94063, USA. timothy.hoey@gmail.com.

Sci Rep ; 7(1): 15270, 2017 11 10.

Article de En | MEDLINE | ID: mdl-29127379

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Composés pontés / Tumeurs colorectales / Paclitaxel / Thrombospondines / Taxoïdes / Microenvironnement tumoral / Voie de signalisation Wnt / Mutation / Protéines tumorales Type d'étude: Prognostic_studies Limites: Animals Langue: En Journal: Sci Rep Année: 2017 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: Royaume-Uni

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