Targeting negative regulation of p53 by MDM2 and WIP1 as a therapeutic strategy in cutaneous melanoma.

Wu, Chiao-En; Esfandiari, Arman; Ho, Yi-Hsuan; Wang, Nan; Mahdi, Ahmed Khairallah; Aptullahoglu, Erhan; Lovat, Penny; Lunec, John

Wu, Chiao-En; Esfandiari, Arman; Ho, Yi-Hsuan; Wang, Nan; Mahdi, Ahmed Khairallah; Aptullahoglu, Erhan; Lovat, Penny; Lunec, John.

Affiliation

Wu CE; Northern Institute for Cancer Research, School of Medicine, Newcastle University, Paul O'Gorman Building, Framlington Place, Newcastle-upon-Tyne NE2 4HH, UK.
Esfandiari A; Division of Hematology-Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, Taoyuan 333, Taiwan.
Ho YH; Northern Institute for Cancer Research, School of Medicine, Newcastle University, Paul O'Gorman Building, Framlington Place, Newcastle-upon-Tyne NE2 4HH, UK.
Wang N; Northern Institute for Cancer Research, School of Medicine, Newcastle University, Paul O'Gorman Building, Framlington Place, Newcastle-upon-Tyne NE2 4HH, UK.
Mahdi AK; Arraygen UK Ltd, Devonshire Building, Newcastle University, Newcastle-upon-Tyne NE1 7RU, UK.
Aptullahoglu E; Northern Institute for Cancer Research, School of Medicine, Newcastle University, Paul O'Gorman Building, Framlington Place, Newcastle-upon-Tyne NE2 4HH, UK.
Lovat P; Department of Pathology and Forensic Medicine, College of Medicine, Al-Nahrain University, Baghdad 10006, Iraq.
Lunec J; Northern Institute for Cancer Research, School of Medicine, Newcastle University, Paul O'Gorman Building, Framlington Place, Newcastle-upon-Tyne NE2 4HH, UK.

Br J Cancer ; 118(4): 495-508, 2018 02 20.

Article de En | MEDLINE | ID: mdl-29235570

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Tumeurs cutanées / Mutagenèse dirigée / Protéine p53 suppresseur de tumeur / Dipeptides / Aminopyridines / Mélanome Limites: Humans Langue: En Journal: Br J Cancer Année: 2018 Type de document: Article Pays d'affiliation: Royaume-Uni

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