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Genetic and epigenetic regulation of PPARγ during adipogenesis.
Cui, Ting-Ting; Xing, Tian-Yu; Chu, Yan-Kan; Li, Hui; Wang, Ning.
Affiliation
  • Cui TT; 1. Key Laboratory of Chicken Genetics and Breeding, Ministry of Agriculture, Harbin 150030, China; 2. Key Laboratory of Animal Genetics, Breeding and Reproduction, Education Department of Heilongjiang Province, Harbin 150030, China; 3. Key Laboratory of Animal Cells and Genetic Engineering of Heilon
  • Xing TY; 1. Key Laboratory of Chicken Genetics and Breeding, Ministry of Agriculture, Harbin 150030, China; 2. Key Laboratory of Animal Genetics, Breeding and Reproduction, Education Department of Heilongjiang Province, Harbin 150030, China; 3. Key Laboratory of Animal Cells and Genetic Engineering of Heilon
  • Chu YK; 1. Key Laboratory of Chicken Genetics and Breeding, Ministry of Agriculture, Harbin 150030, China; 2. Key Laboratory of Animal Genetics, Breeding and Reproduction, Education Department of Heilongjiang Province, Harbin 150030, China; 3. Key Laboratory of Animal Cells and Genetic Engineering of Heilon
  • Li H; 1. Key Laboratory of Chicken Genetics and Breeding, Ministry of Agriculture, Harbin 150030, China; 2. Key Laboratory of Animal Genetics, Breeding and Reproduction, Education Department of Heilongjiang Province, Harbin 150030, China; 3. Key Laboratory of Animal Cells and Genetic Engineering of Heilon
  • Wang N; 1. Key Laboratory of Chicken Genetics and Breeding, Ministry of Agriculture, Harbin 150030, China; 2. Key Laboratory of Animal Genetics, Breeding and Reproduction, Education Department of Heilongjiang Province, Harbin 150030, China; 3. Key Laboratory of Animal Cells and Genetic Engineering of Heilon
Yi Chuan ; 39(11): 1066-1077, 2017 Nov 20.
Article de En | MEDLINE | ID: mdl-29254924
Peroxisome proliferator-activated receptor gamma (PPARγ) is the master regulator of adipogenesis and adipose tissue development. It also plays crucial roles in many other biological processes, including lipid and glucose metabolism and energy homeostasis. Recently, evidence has been accumulating that the PPARγ gene is not only genetically regulated, but also epigenetically regulated by DNA methylation, histone modification, non-coding RNA and chromosome remodeling. In this review, we summarize the advances in the genetic and epigenetic regulation of the PPARγ gene during adipogenesis, and discuss future research directions and trends for the study of its regulation.
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Méthylation de l'ADN / Récepteur PPAR gamma / Adipogenèse Limites: Animals / Humans Langue: En Journal: Yi Chuan Sujet du journal: GENETICA Année: 2017 Type de document: Article Pays de publication: Chine
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Méthylation de l'ADN / Récepteur PPAR gamma / Adipogenèse Limites: Animals / Humans Langue: En Journal: Yi Chuan Sujet du journal: GENETICA Année: 2017 Type de document: Article Pays de publication: Chine