Radiation induced violations of blood circulation in the ciliary body and changes of the anterior chamber angle in the pathogenesis of glaucoma in clean up workers of the Chornobyl NPP accident and residents of contaminated areas. / RADITsIYÌNO INDUKOVANI PORUShENNIa KROVOOBIGU V TsILIARNOMU TILI TA ZMINY KUTA PEREDN'OI KAMERY OKA V PATOGENEZI GLAUKOMY V UChASNYKIV AVARIYÌNYKh ROBIT NA ChORNOBYL'S'KIYÌ AES I MEShKANTsIV ZABRUDNENYKh TERYTORIYÌ.
Probl Radiac Med Radiobiol
; 22: 332-338, 2017 Dec.
Article
de En, Uk
| MEDLINE
| ID: mdl-29286518
ABSTRACT
OBJECTIVE:
Estimate changes blood filling of the ciliary body and changes of the anterior chamber angle; study their influence to glaucoma pathogenesis in irradiated persons. MATERIALS ANDMETHODS:
Used the results of a randomly selected group survey of 41 clean up workers of the Chornobyl NPP accident (clean up workers), and 18 inhabitants of the zone of guaranteed voluntary resettlement; age at the time of the survey was 45-50 years. The control group consisted of 41 persons of the same age had not radiation exposure. State of the anterior chamber angle studied by gonioscopy, which was conducted 35 clean up workers and 35 persons of the control group. Changes of the blood circulation in the ciliary body examine by the ophtalmoreog raphy, what was done on 12 eyes of 6 clean up workers, control was 12 eyes of 6 persons had not radiation exposure.RESULTS:
Detection revealed of the blood circulation in the ciliary body in all clean up workers, reography coefficient was probably lower (p < 0.05), than in the control group. The research of the state of the anterior chamber angle revealed a higher relative risk of appearance of involution changes of the anterior chamber angle in clean up work ers of ChNPP accident, in comparison with the control group was 3.5 (1.27; 9.5) χ2 = 7.48, p = 0.031. The same changes are characteristic for inhabitants of radiation polluted territories.CONCLUSIONS:
Influence ionizing radiation causes a blood circulation decrease in the ciliary body and development changes of the angle of the anterior chamber. Presence of these changes can explain the features of the pathogene sis of glaucoma in irradiated late manifestation and, at the same time, severe course.Mots clés
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Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Lésions radiques
/
Glaucome
/
Corps ciliaire
/
Exposition professionnelle
/
Exposition aux rayonnements
/
Accident nucléaire de Tchernobyl
/
Chambre antérieure du bulbe oculaire
Type d'étude:
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Limites:
Adult
/
Humans
/
Male
/
Middle aged
Pays/Région comme sujet:
Europa
Langue:
En
/
Uk
Journal:
Probl Radiac Med Radiobiol
Année:
2017
Type de document:
Article
Pays d'affiliation:
Ukraine