Translation Termination Factor GSPT1 Is a Phenotypically Relevant Off-Target of Heterobifunctional Phthalimide Degraders.

Ishoey, Mette; Chorn, Someth; Singh, Natesh; Jaeger, Martin G; Brand, Matthias; Paulk, Joshiawa; Bauer, Sophie; Erb, Michael A; Parapatics, Katja; Müller, André C; Bennett, Keiryn L; Ecker, Gerhard F; Bradner, James E; Winter, Georg E

Ishoey, Mette; Chorn, Someth; Singh, Natesh; Jaeger, Martin G; Brand, Matthias; Paulk, Joshiawa; Bauer, Sophie; Erb, Michael A; Parapatics, Katja; Müller, André C; Bennett, Keiryn L; Ecker, Gerhard F; Bradner, James E; Winter, Georg E.

Affiliation

Ishoey M; Department of Medical Oncology , Dana-Farber Cancer Institute , Boston , Massachusetts 02115 , United States.
Chorn S; CeMM Research Center for Molecular Medicine of the Austrian Academy of Science , Lazarettgasse 14, AKH Bt. 25.3 , 1090 Vienna , Austria.
Singh N; University of Vienna , Department of Pharmaceutical Chemistry , Althanstrasse 14 , 1090 Vienna , Austria.
Jaeger MG; CeMM Research Center for Molecular Medicine of the Austrian Academy of Science , Lazarettgasse 14, AKH Bt. 25.3 , 1090 Vienna , Austria.
Brand M; CeMM Research Center for Molecular Medicine of the Austrian Academy of Science , Lazarettgasse 14, AKH Bt. 25.3 , 1090 Vienna , Austria.
Paulk J; Department of Medical Oncology , Dana-Farber Cancer Institute , Boston , Massachusetts 02115 , United States.
Bauer S; Novartis Institutes for Biomedical Research , Cambridge , Massachusetts 02139 , United States.
Erb MA; CeMM Research Center for Molecular Medicine of the Austrian Academy of Science , Lazarettgasse 14, AKH Bt. 25.3 , 1090 Vienna , Austria.
Parapatics K; Department of Medical Oncology , Dana-Farber Cancer Institute , Boston , Massachusetts 02115 , United States.
Müller AC; CeMM Research Center for Molecular Medicine of the Austrian Academy of Science , Lazarettgasse 14, AKH Bt. 25.3 , 1090 Vienna , Austria.
Bennett KL; CeMM Research Center for Molecular Medicine of the Austrian Academy of Science , Lazarettgasse 14, AKH Bt. 25.3 , 1090 Vienna , Austria.
Ecker GF; CeMM Research Center for Molecular Medicine of the Austrian Academy of Science , Lazarettgasse 14, AKH Bt. 25.3 , 1090 Vienna , Austria.
Bradner JE; University of Vienna , Department of Pharmaceutical Chemistry , Althanstrasse 14 , 1090 Vienna , Austria.
Winter GE; Department of Medical Oncology , Dana-Farber Cancer Institute , Boston , Massachusetts 02115 , United States.

ACS Chem Biol ; 13(3): 553-560, 2018 03 16.

Article de En | MEDLINE | ID: mdl-29356495

Sujet(s)

Texte intégral

Ajouter à My VHL

Imprimer

XML

PubMed Links

Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Terminaison de la traduction / Facteurs terminaison chaîne peptidique / Protéolyse Type d'étude: Prognostic_studies Limites: Humans Langue: En Journal: ACS Chem Biol Année: 2018 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: États-Unis d'Amérique

Texte intégral

Ajouter à My VHL

Imprimer

XML

PubMed Links

Recherche sur Google