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Knockdown of wfs1, a fly homolog of Wolfram syndrome 1, in the nervous system increases susceptibility to age- and stress-induced neuronal dysfunction and degeneration in Drosophila.
Sakakibara, Yasufumi; Sekiya, Michiko; Fujisaki, Naoki; Quan, Xiuming; Iijima, Koichi M.
Affiliation
  • Sakakibara Y; Department of Alzheimer's Disease Research, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan.
  • Sekiya M; Department of Alzheimer's Disease Research, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan.
  • Fujisaki N; Department of Alzheimer's Disease Research, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan.
  • Quan X; Department of Experimental Gerontology, Graduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabe-dori, Mizuho-ku, Nagoya, Japan.
  • Iijima KM; Department of Alzheimer's Disease Research, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan.
PLoS Genet ; 14(1): e1007196, 2018 01.
Article de En | MEDLINE | ID: mdl-29357349

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Drosophila melanogaster / Protéines membranaires / Troubles mentaux / Dégénérescence nerveuse / Système nerveux Type d'étude: Diagnostic_studies Limites: Animals / Humans Langue: En Journal: PLoS Genet Sujet du journal: GENETICA Année: 2018 Type de document: Article Pays d'affiliation: Japon Pays de publication: États-Unis d'Amérique

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Drosophila melanogaster / Protéines membranaires / Troubles mentaux / Dégénérescence nerveuse / Système nerveux Type d'étude: Diagnostic_studies Limites: Animals / Humans Langue: En Journal: PLoS Genet Sujet du journal: GENETICA Année: 2018 Type de document: Article Pays d'affiliation: Japon Pays de publication: États-Unis d'Amérique