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Three new Lycopodium alkaloids from Lycopodium japonicum.
Zhu, Yu; Dong, Liao-Bin; Zhang, Zhi-Jun; Fan, Min; Zhu, Qin-Feng; Qi, Yan-Yan; Liu, Yu-Chen; Peng, Li-Yan; Wu, Xing-De; Zhao, Qin-Shi.
Affiliation
  • Zhu Y; a State Key Laboratory of Phytochemistry and Plant Resources in West China , Kunming Institute of Botany, Chinese Academy of Sciences , Kunming 650204 , China.
  • Dong LB; b University of the Chinese Academy of Sciences , Beijing 100049 , China.
  • Zhang ZJ; a State Key Laboratory of Phytochemistry and Plant Resources in West China , Kunming Institute of Botany, Chinese Academy of Sciences , Kunming 650204 , China.
  • Fan M; a State Key Laboratory of Phytochemistry and Plant Resources in West China , Kunming Institute of Botany, Chinese Academy of Sciences , Kunming 650204 , China.
  • Zhu QF; b University of the Chinese Academy of Sciences , Beijing 100049 , China.
  • Qi YY; a State Key Laboratory of Phytochemistry and Plant Resources in West China , Kunming Institute of Botany, Chinese Academy of Sciences , Kunming 650204 , China.
  • Liu YC; a State Key Laboratory of Phytochemistry and Plant Resources in West China , Kunming Institute of Botany, Chinese Academy of Sciences , Kunming 650204 , China.
  • Peng LY; b University of the Chinese Academy of Sciences , Beijing 100049 , China.
  • Wu XD; a State Key Laboratory of Phytochemistry and Plant Resources in West China , Kunming Institute of Botany, Chinese Academy of Sciences , Kunming 650204 , China.
  • Zhao QS; b University of the Chinese Academy of Sciences , Beijing 100049 , China.
J Asian Nat Prod Res ; 21(1): 17-24, 2019 Jan.
Article de En | MEDLINE | ID: mdl-29373928
ABSTRACT
Three new Lycopodium alkaloids (1-3), together with 15 known alkaloids, were isolated from club moss Lycopodium japonicum. Their structures were determined by extensive spectroscopic analysis, including 1D and 2D NMR spectra. Compound 1 has an unusual ß-oriented methyl group substituted at C-15 and an α-hydroxy cyclopentenone moiety. All new alkaloids were evaluated for the inhibition of T-type calcium channel.
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Lycopodium / Alcaloïdes Limites: Humans Langue: En Journal: J Asian Nat Prod Res Sujet du journal: BOTANICA / QUIMICA Année: 2019 Type de document: Article Pays d'affiliation: Chine

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Lycopodium / Alcaloïdes Limites: Humans Langue: En Journal: J Asian Nat Prod Res Sujet du journal: BOTANICA / QUIMICA Année: 2019 Type de document: Article Pays d'affiliation: Chine