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Nuclear translocation of IGF1R by intracellular amphiregulin contributes to the resistance of lung tumour cells to EGFR-TKI.
Guerard, Marie; Robin, Thomas; Perron, Pascal; Hatat, Anne-Sophie; David-Boudet, Laurence; Vanwonterghem, Laetitia; Busser, Benoit; Coll, Jean-Luc; Lantuejoul, Sylvie; Eymin, Beatrice; Hurbin, Amandine; Gazzeri, Sylvie.
Affiliation
  • Guerard M; Team "RNA splicing, cell signalling and response to therapies", Univ. Grenoble Alpes, INSERM U1209, CNRS UMR 5309, Institute for Advanced Biosciences, 38000 Grenoble, France; Team "Cancer targets and experimental therapeutics", Univ. Grenoble Alpes, INSERM U1209, CNRS UMR 5309, Institute for Advance
  • Robin T; Team "RNA splicing, cell signalling and response to therapies", Univ. Grenoble Alpes, INSERM U1209, CNRS UMR 5309, Institute for Advanced Biosciences, 38000 Grenoble, France; Team "Cancer targets and experimental therapeutics", Univ. Grenoble Alpes, INSERM U1209, CNRS UMR 5309, Institute for Advance
  • Perron P; Team "RNA splicing, cell signalling and response to therapies", Univ. Grenoble Alpes, INSERM U1209, CNRS UMR 5309, Institute for Advanced Biosciences, 38000 Grenoble, France; Team "Cancer targets and experimental therapeutics", Univ. Grenoble Alpes, INSERM U1209, CNRS UMR 5309, Institute for Advance
  • Hatat AS; Team "RNA splicing, cell signalling and response to therapies", Univ. Grenoble Alpes, INSERM U1209, CNRS UMR 5309, Institute for Advanced Biosciences, 38000 Grenoble, France. Electronic address: anne-sophie.hatat@univ-grenoble-alpes.fr.
  • David-Boudet L; Grenoble Univ. Hospital, 38000 Grenoble France. Electronic address: LDavid-boudet@chu-grenoble.fr.
  • Vanwonterghem L; Team "Cancer targets and experimental therapeutics", Univ. Grenoble Alpes, INSERM U1209, CNRS UMR 5309, Institute for Advanced Biosciences, 38000 Grenoble, France. Electronic address: laetitia.vanwonterghem@univ-grenoble-alpes.fr.
  • Busser B; Team "Cancer targets and experimental therapeutics", Univ. Grenoble Alpes, INSERM U1209, CNRS UMR 5309, Institute for Advanced Biosciences, 38000 Grenoble, France; Grenoble Univ. Hospital, 38000 Grenoble France. Electronic address: BBusser@chu-grenoble.fr.
  • Coll JL; Team "Cancer targets and experimental therapeutics", Univ. Grenoble Alpes, INSERM U1209, CNRS UMR 5309, Institute for Advanced Biosciences, 38000 Grenoble, France. Electronic address: jean-luc.coll@univ-grenoble-alpes.fr.
  • Lantuejoul S; Grenoble Univ. Hospital, 38000 Grenoble France. Electronic address: SLantuejoul@chu-grenoble.fr.
  • Eymin B; Team "RNA splicing, cell signalling and response to therapies", Univ. Grenoble Alpes, INSERM U1209, CNRS UMR 5309, Institute for Advanced Biosciences, 38000 Grenoble, France. Electronic address: Beatrice.Eymin@univ-grenoble-alpes.fr.
  • Hurbin A; Team "Cancer targets and experimental therapeutics", Univ. Grenoble Alpes, INSERM U1209, CNRS UMR 5309, Institute for Advanced Biosciences, 38000 Grenoble, France. Electronic address: amandine.hurbin@inserm.fr.
  • Gazzeri S; Team "RNA splicing, cell signalling and response to therapies", Univ. Grenoble Alpes, INSERM U1209, CNRS UMR 5309, Institute for Advanced Biosciences, 38000 Grenoble, France. Electronic address: Sylvie.Gazzeri@univ-grenoble-alpes.fr.
Cancer Lett ; 420: 146-155, 2018 04 28.
Article de En | MEDLINE | ID: mdl-29421153

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Noyau de la cellule / Récepteurs des somatomédines / Adénocarcinome mucineux / Résistance aux médicaments antinéoplasiques / Amphiréguline / Tumeurs du poumon Type d'étude: Prognostic_studies Limites: Humans Langue: En Journal: Cancer Lett Année: 2018 Type de document: Article Pays de publication: Irlande

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Noyau de la cellule / Récepteurs des somatomédines / Adénocarcinome mucineux / Résistance aux médicaments antinéoplasiques / Amphiréguline / Tumeurs du poumon Type d'étude: Prognostic_studies Limites: Humans Langue: En Journal: Cancer Lett Année: 2018 Type de document: Article Pays de publication: Irlande