Current state of risk stratification for sudden cardiac death in adults with congenital heart disease.
Anatol J Cardiol
; 19(6): 401-403, 2018 Jun.
Article
de En
| MEDLINE
| ID: mdl-29537971
ABSTRACT
Sudden cardiac death (SCD), mainly caused by ventricular arrhythmias, is one of the leading causes of mortality in adult congenital heart disease (ACHD) patients. An implantable cardioverter defibrillator (ICD) may prevent SCD, but risk stratification remains challenging. In this review, we will address the current guideline recommendations for ICD implantation in ACHD patients, as well as review a recent study in which the discriminative ability for SCD of these guidelines is evaluated. In this study, the guideline recommendations were applied to patients who died of SCD and living controls. Among SCD cases, 35%-41% of patients were recommended ICD, whereas 16%-17% of controls were recommended ICD. The discriminative ability for SCD of the guidelines was poor, with an area under the receiver operating characteristic curve of 0.61-0.63. Risk stratification for SCD in ACHD patients, therefore, remains to be a work-in-progress.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Mort subite cardiaque
/
Cardiopathies congénitales
Type d'étude:
Etiology_studies
/
Guideline
/
Prognostic_studies
/
Risk_factors_studies
Limites:
Adult
/
Humans
Langue:
En
Journal:
Anatol J Cardiol
Année:
2018
Type de document:
Article