New insights in dermatophyte research.
Med Mycol
; 56(suppl_1): 2-9, 2018 Apr 01.
Article
de En
| MEDLINE
| ID: mdl-29538740
ABSTRACT
Dermatophyte research has renewed interest because of changing human floras with changing socioeconomic conditions, and because of severe chronic infections in patients with congenital immune disorders. Main taxonomic traits at the generic level have changed considerably, and now fine-tuning at the species level with state-of-the-art technology has become urgent. Research on virulence factors focuses on secreted proteases now has support in genome data. It is speculated that most protease families are used for degrading hard keratin during nitrogen recycling in the environment, while others, such as Sub6 may have emerged as a result of ancestral gene duplication, and are likely to have specific roles during infection. Virulence may differ between mating partners of the same species and concepts of zoo- and anthropophily may require revision in some recently redefined species. Many of these questions benefit from international cooperation and exchange of materials. The aim of the ISHAM Working Group Dermatophytes aims to stimulate and coordinate international networking on these fungi.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Mycoses cutanées
/
Champignons
Limites:
Animals
/
Humans
Langue:
En
Journal:
Med Mycol
Sujet du journal:
MEDICINA VETERINARIA
/
MICROBIOLOGIA
Année:
2018
Type de document:
Article
Pays d'affiliation:
Allemagne