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Pseudoneutropenia in lymphangioleiomyomatosis (LAM) patients receiving sirolimus: evaluation in a 100 patient cohort.
Gopalakrishnan, Vissagan; Jones, Amanda M; Julien-Williams, Patricia; Machado, Tania; Danner, Robert L; Swigris, Jeffrey J; Paine, Robert; Lozier, Jay N; Moss, Joel.
Affiliation
  • Gopalakrishnan V; Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
  • Jones AM; Rush Medical College, Rush University Medical Center, Chicago, IL, USA.
  • Julien-Williams P; Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
  • Machado T; Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
  • Danner RL; Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
  • Swigris JJ; Critical Care Medicine Dept, NIH Clinical Center, Bethesda, MD, USA.
  • Paine R; Division of Pulmonary, Critical Care and Sleep Medicine, National Jewish Health, Denver, CO, USA.
  • Lozier JN; Division of Respiratory, Critical Care and Occupational Pulmonary Medicine, Dept of Internal Medicine, University of Utah Health Sciences Center, Salt Lake City, UT, USA.
  • Moss J; Dept of Laboratory Medicine, NIH Clinical Center, Bethesda, MD, USA.
ERJ Open Res ; 4(1)2018 Jan.
Article de En | MEDLINE | ID: mdl-29577040
ABSTRACT
In lymphangioleiomyomatosis patients receiving sirolimus treatment, transient leukopenia in the morning may be due to circadian rhythm, with leukocyte counts recovering later in the day, indicating that a decrease in drug dose may not be warranted http//ow.ly/jPFz30iysgV.

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Langue: En Journal: ERJ Open Res Année: 2018 Type de document: Article Pays d'affiliation: États-Unis d'Amérique

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Langue: En Journal: ERJ Open Res Année: 2018 Type de document: Article Pays d'affiliation: États-Unis d'Amérique