Why, who and when to start treatment for chronic hepatitis B infection.
Curr Opin Virol
; 30: 39-47, 2018 06.
Article
de En
| MEDLINE
| ID: mdl-29655092
ABSTRACT
Chronic hepatitis B remains a major global health challenge due to morbidity and mortality from hepatocellular carcinoma and complications of liver cirrhosis. Current treatment regimens are non-curative and, once initiated, treatment is of indefinite duration for the majority. The decision to initiate treatment decisions is based on risk stratification. Advances in our understanding of the natural history of chronic hepatitis B have led to a paradigm shift in recommendations for treatment. Emerging non-invasive biomarkers of disease activity will further enhance disease stratification. In this review, we summarise the guidance from major international societies on treatment for chronic hepatitis B and explore some of the novel approaches to disease assessment.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Antiviraux
/
Carcinome hépatocellulaire
/
Prise en charge de la maladie
/
Hépatite B chronique
Type d'étude:
Guideline
/
Prognostic_studies
Limites:
Humans
Langue:
En
Journal:
Curr Opin Virol
Année:
2018
Type de document:
Article
Pays d'affiliation:
Royaume-Uni