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Caspase-1 inhibition prevents glial inflammasome activation and pyroptosis in models of multiple sclerosis.
McKenzie, Brienne A; Mamik, Manmeet K; Saito, Leina B; Boghozian, Roobina; Monaco, Maria Chiara; Major, Eugene O; Lu, Jian-Qiang; Branton, William G; Power, Christopher.
Affiliation
  • McKenzie BA; Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, AB T6G 2R3, Canada.
  • Mamik MK; Division of Neurology, Department of Medicine, University of Alberta, Edmonton, AB T6G 2R3, Canada.
  • Saito LB; Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, AB T6G 2R3, Canada.
  • Boghozian R; Division of Neurology, Department of Medicine, University of Alberta, Edmonton, AB T6G 2R3, Canada.
  • Monaco MC; Department of Immunology, Tehran University of Medical Sciences, Tehran 1417653761, Iran.
  • Major EO; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892.
  • Lu JQ; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892.
  • Branton WG; Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB T6G 2R3, Canada.
  • Power C; Neuroscience and Mental Health Institute, University of Alberta, Edmonton, AB T6G 2R3, Canada.
Proc Natl Acad Sci U S A ; 115(26): E6065-E6074, 2018 06 26.
Article de En | MEDLINE | ID: mdl-29895691
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Oligodendroglie / Caspase-1 / Dipeptides / Para-Aminobenzoates / Inhibiteurs des caspases / Pyroptose / Modèles biologiques / Sclérose en plaques Limites: Humans Langue: En Journal: Proc Natl Acad Sci U S A Année: 2018 Type de document: Article Pays d'affiliation: Canada
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Oligodendroglie / Caspase-1 / Dipeptides / Para-Aminobenzoates / Inhibiteurs des caspases / Pyroptose / Modèles biologiques / Sclérose en plaques Limites: Humans Langue: En Journal: Proc Natl Acad Sci U S A Année: 2018 Type de document: Article Pays d'affiliation: Canada