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Differentiated macrophages acquire a pro-inflammatory and cell death-resistant phenotype due to increasing XIAP and p38-mediated inhibition of RipK1.
Rijal, Dikchha; Ariana, Ardeshir; Wight, Andrew; Kim, Kwangsin; Alturki, Norah A; Aamir, Zoya; Ametepe, Emmanuelle S; Korneluk, Robert G; Tiedje, Christopher; Menon, Manoj B; Gaestel, Matthias; McComb, Scott; Sad, Subash.
Affiliation
  • Rijal D; From the Department of Biochemistry, Microbiology, and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario K1H 8M8, Canada.
  • Ariana A; From the Department of Biochemistry, Microbiology, and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario K1H 8M8, Canada.
  • Wight A; From the Department of Biochemistry, Microbiology, and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario K1H 8M8, Canada.
  • Kim K; From the Department of Biochemistry, Microbiology, and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario K1H 8M8, Canada.
  • Alturki NA; From the Department of Biochemistry, Microbiology, and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario K1H 8M8, Canada.
  • Aamir Z; From the Department of Biochemistry, Microbiology, and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario K1H 8M8, Canada.
  • Ametepe ES; From the Department of Biochemistry, Microbiology, and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario K1H 8M8, Canada.
  • Korneluk RG; the Children's Hospital of Eastern Ontario Research Institute, Ottawa, Ontario K1H 5B2, Canada.
  • Tiedje C; the Institute of Cell Biochemistry, Hannover Medical School, 30625 Hannover, Germany.
  • Menon MB; the Department of Cellular and Molecular Medicine, University of Copenhagen, 1165 Copenhagen, Denmark.
  • Gaestel M; the Institute of Cell Biochemistry, Hannover Medical School, 30625 Hannover, Germany.
  • McComb S; the Institute of Cell Biochemistry, Hannover Medical School, 30625 Hannover, Germany.
  • Sad S; the Human Health Therapeutics Research Centre, National Research Council of Canada, Ottawa K1A 0R6, Ontario, Canada, and.
J Biol Chem ; 293(30): 11913-11927, 2018 07 27.
Article de En | MEDLINE | ID: mdl-29899110
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: P38 Mitogen-Activated Protein Kinases / Protéines IAP / Receptor-Interacting Protein Serine-Threonine Kinases / Inflammation / Macrophages Limites: Animals Langue: En Journal: J Biol Chem Année: 2018 Type de document: Article Pays d'affiliation: Canada Pays de publication: États-Unis d'Amérique
Texte intégral
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: P38 Mitogen-Activated Protein Kinases / Protéines IAP / Receptor-Interacting Protein Serine-Threonine Kinases / Inflammation / Macrophages Limites: Animals Langue: En Journal: J Biol Chem Année: 2018 Type de document: Article Pays d'affiliation: Canada Pays de publication: États-Unis d'Amérique