Early cell death induced by Clostridium difficile TcdB: Uptake and Rac1-glucosylation kinetics are decisive for cell fate.

Beer, Lara-Antonia; Tatge, Helma; Reich, Nicole; Tenspolde, Michel; Olling, Alexandra; Goy, Sebastian; Rottner, Klemens; Alekov, Alexi Kirilov; Gerhard, Ralf

Beer, Lara-Antonia; Tatge, Helma; Reich, Nicole; Tenspolde, Michel; Olling, Alexandra; Goy, Sebastian; Rottner, Klemens; Alekov, Alexi Kirilov; Gerhard, Ralf.

Affiliation

Beer LA; Institute of Toxicology, Hannover Medical School, Hannover, Germany.
Tatge H; Institute of Toxicology, Hannover Medical School, Hannover, Germany.
Reich N; Institute of Toxicology, Hannover Medical School, Hannover, Germany.
Tenspolde M; Institute of Toxicology, Hannover Medical School, Hannover, Germany.
Olling A; Institute of Toxicology, Hannover Medical School, Hannover, Germany.
Goy S; Institute of Toxicology, Hannover Medical School, Hannover, Germany.
Rottner K; Division of Molecular Cell Biology, Zoological Institute, Braunschweig, Germany.
Alekov AK; Molecular Cell Biology Group, Helmholtz Centre for Infection Research, Braunschweig, Germany.
Gerhard R; Institute for Neurophysiology, Hannover Medical School, Hannover, Germany.

Cell Microbiol ; 20(10): e12865, 2018 10.

Article de En | MEDLINE | ID: mdl-29904993

Sujet(s)
Mots clés

cell death; cellular uptake; clostridium difficile; reactive oxygen species; toxins

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Protéines bactériennes / Toxines bactériennes / Clostridioides difficile / Apoptose / Antiport des ions sodium-hydrogène / Protéine G rac1 Limites: Humans Langue: En Journal: Cell Microbiol Sujet du journal: MICROBIOLOGIA Année: 2018 Type de document: Article Pays d'affiliation: Allemagne Pays de publication: Inde

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