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Multifunctional Pan-ebolavirus Antibody Recognizes a Site of Broad Vulnerability on the Ebolavirus Glycoprotein.
Gilchuk, Pavlo; Kuzmina, Natalia; Ilinykh, Philipp A; Huang, Kai; Gunn, Bronwyn M; Bryan, Aubrey; Davidson, Edgar; Doranz, Benjamin J; Turner, Hannah L; Fusco, Marnie L; Bramble, Matthew S; Hoff, Nicole A; Binshtein, Elad; Kose, Nurgun; Flyak, Andrew I; Flinko, Robin; Orlandi, Chiara; Carnahan, Robert; Parrish, Erica H; Sevy, Alexander M; Bombardi, Robin G; Singh, Prashant K; Mukadi, Patrick; Muyembe-Tamfum, Jean Jacques; Ohi, Melanie D; Saphire, Erica Ollmann; Lewis, George K; Alter, Galit; Ward, Andrew B; Rimoin, Anne W; Bukreyev, Alexander; Crowe, James E.
Affiliation
  • Gilchuk P; Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
  • Kuzmina N; Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA; Galveston National Laboratory, Galveston, TX 77550, USA.
  • Ilinykh PA; Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA; Galveston National Laboratory, Galveston, TX 77550, USA.
  • Huang K; Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA; Galveston National Laboratory, Galveston, TX 77550, USA.
  • Gunn BM; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA.
  • Bryan A; Integral Molecular, Inc., Philadelphia, PA 19104, USA.
  • Davidson E; Integral Molecular, Inc., Philadelphia, PA 19104, USA.
  • Doranz BJ; Integral Molecular, Inc., Philadelphia, PA 19104, USA.
  • Turner HL; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Fusco ML; The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Bramble MS; Department of Epidemiology, Jonathan and Karin Fielding School of Public Health, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Genetic Medicine Research, Children's Research Institute, Children's National Medical Center, Washington, DC 20010, USA.
  • Hoff NA; Department of Epidemiology, Jonathan and Karin Fielding School of Public Health, University of California, Los Angeles, Los Angeles, CA 90095, USA.
  • Binshtein E; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN 37232, USA.
  • Kose N; Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
  • Flyak AI; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
  • Flinko R; Division of Vaccine Research, Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
  • Orlandi C; Division of Vaccine Research, Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
  • Carnahan R; Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
  • Parrish EH; Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
  • Sevy AM; Chemical and Physical Biology Program, Vanderbilt University, Nashville, TN 37232, USA.
  • Bombardi RG; Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
  • Singh PK; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN 37232, USA.
  • Mukadi P; Institut Nationale de Recherche Biomédicale, Kinshasa, Democratic Republic of the Congo.
  • Muyembe-Tamfum JJ; Institut Nationale de Recherche Biomédicale, Kinshasa, Democratic Republic of the Congo.
  • Ohi MD; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN 37232, USA.
  • Saphire EO; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La J
  • Lewis GK; Division of Vaccine Research, Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
  • Alter G; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA.
  • Ward AB; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Rimoin AW; Department of Epidemiology, Jonathan and Karin Fielding School of Public Health, University of California, Los Angeles, Los Angeles, CA 90095, USA.
  • Bukreyev A; Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA; Galveston National Laboratory, Galveston, TX 77550, USA; Department of Microbiology & Immunology, University of Texas Medical Branch, Galveston, TX 77555, USA. Electronic address: alexander.bukreyev@utmb.edu.
  • Crowe JE; Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Chemical and Physical Biology Program, Vanderbilt University, Nashville, TN 37232, USA; De
Immunity ; 49(2): 363-374.e10, 2018 08 21.
Article de En | MEDLINE | ID: mdl-30029854

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Glycoprotéines / Fièvre hémorragique à virus Ebola / Ebolavirus / Anticorps neutralisants / Anticorps monoclonaux / Anticorps antiviraux Limites: Adult / Animals / Female / Humans / Male Langue: En Journal: Immunity Sujet du journal: ALERGIA E IMUNOLOGIA Année: 2018 Type de document: Article Pays d'affiliation: États-Unis d'Amérique

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Glycoprotéines / Fièvre hémorragique à virus Ebola / Ebolavirus / Anticorps neutralisants / Anticorps monoclonaux / Anticorps antiviraux Limites: Adult / Animals / Female / Humans / Male Langue: En Journal: Immunity Sujet du journal: ALERGIA E IMUNOLOGIA Année: 2018 Type de document: Article Pays d'affiliation: États-Unis d'Amérique