<i>N</i>-Acetyl-3-aminopyrazoles block the non-canonical NF-kB cascade by selectively inhibiting NIK.

Pippione, Agnese C; Sainas, Stefano; Federico, Antonella; Lupino, Elisa; Piccinini, Marco; Kubbutat, Michael; Contreras, Jean-Marie; Morice, Christophe; Barge, Alessandro; Ducime, Alex; Boschi, Donatella; Al-Karadaghi, Salam; Lolli, Marco L

N-Acetyl-3-aminopyrazoles block the non-canonical NF-kB cascade by selectively inhibiting NIK.

Pippione, Agnese C; Sainas, Stefano; Federico, Antonella; Lupino, Elisa; Piccinini, Marco; Kubbutat, Michael; Contreras, Jean-Marie; Morice, Christophe; Barge, Alessandro; Ducime, Alex; Boschi, Donatella; Al-Karadaghi, Salam; Lolli, Marco L.

Affiliation

Pippione AC; Department of Science and Drug Technology , University of Torino , via Pietro Giuria 9 , 10125 Torino , Italy . Email: marco.lolli@unito.it.
Sainas S; Department of Science and Drug Technology , University of Torino , via Pietro Giuria 9 , 10125 Torino , Italy . Email: marco.lolli@unito.it.
Federico A; Department of Science and Drug Technology , University of Torino , via Pietro Giuria 9 , 10125 Torino , Italy . Email: marco.lolli@unito.it.
Lupino E; Department of Oncology , University of Torino , via Michelangelo 27/B , 10126 Torino , Italy.
Piccinini M; Department of Oncology , University of Torino , via Michelangelo 27/B , 10126 Torino , Italy.
Kubbutat M; ProQinase GmbH , Breisacher Str. 117 , 79106 Freiburg , Germany.
Contreras JM; Prestwick Chemical , 220 Boulevard Gonthier d'Andernach , 67400 Illkirch , France.
Morice C; Prestwick Chemical , 220 Boulevard Gonthier d'Andernach , 67400 Illkirch , France.
Barge A; Department of Science and Drug Technology , University of Torino , via Pietro Giuria 9 , 10125 Torino , Italy . Email: marco.lolli@unito.it.
Ducime A; Department of Science and Drug Technology , University of Torino , via Pietro Giuria 9 , 10125 Torino , Italy . Email: marco.lolli@unito.it.
Boschi D; Department of Science and Drug Technology , University of Torino , via Pietro Giuria 9 , 10125 Torino , Italy . Email: marco.lolli@unito.it.
Al-Karadaghi S; SARomics Biostructures , Lund , Sweden.
Lolli ML; Department of Science and Drug Technology , University of Torino , via Pietro Giuria 9 , 10125 Torino , Italy . Email: marco.lolli@unito.it.

Medchemcomm ; 9(6): 963-968, 2018 Jun 01.

Article de En | MEDLINE | ID: mdl-30108985

Texte intégral

Ajouter à My VHL

Imprimer

XML

PubMed Links

Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Langue: En Journal: Medchemcomm Année: 2018 Type de document: Article