Effect of Insulin-Induced Lipodystrophy on Glycemic Control among Children and Adolescents with Diabetes in Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia.
J Diabetes Res
; 2018: 4910962, 2018.
Article
de En
| MEDLINE
| ID: mdl-30116742
ABSTRACT
BACKGROUND:
Lipodystrophy is one of the clinical complications of insulin injection that affects insulin absorption and leads to poor glycemic control.OBJECTIVE:
To assess insulin-induced lipodystrophy and glycemic control.METHODS:
A cross sectional study was done on 176 diabetic children and adolescents who inject insulin for a minimum of one year. First, anthropometric and clinical characteristics of the patients were recorded in questionnaire, and then observation and palpation techniques were used in assessing lipodystrophy.RESULT:
Out of the total 176 participants, 103 (58.5%) had insulin-induced lipodystrophy, of them 100 (97.1%) had lipohypertrophy and 3 (2.9%) had lipoatrophy. Being younger, failure to rotate the injection site every week and multiple reuse of insulin syringe had significant influence in development of insulin-induced lipohypertrophy. Lipohypertrophy in turn was associated with the use of higher dose of insulin and nonoptimal glycemic control.CONCLUSION:
Findings of this study revealed that in spite of using recombinant human insulin, the magnitude of the lipohypertrophy still remained high. Therefore, a routine workup of insulin-injecting patients for such complication is necessary, especially in the individuals who have a nonoptimal glycemic control.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Glycémie
/
Complications du diabète
/
Diabète de type 1
/
Insuline
/
Lipodystrophie
Type d'étude:
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Limites:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Pays/Région comme sujet:
Africa
Langue:
En
Journal:
J Diabetes Res
Année:
2018
Type de document:
Article
Pays d'affiliation:
Éthiopie