Development of a novel UHPLC-MS/MS-based platform to quantify amines, amino acids and methylarginines for applications in human disease phenotyping.

Ahmetaj-Shala, Blerina; Olanipekun, Michael; Tesfai, Abel; MacCallum, Niall; Kirkby, Nicholas S; Quinlan, Gregory J; Shih, Chih-Chin; Kawai, Ryota; Mumby, Sharon; Paul-Clark, Mark; Want, Elizabeth J; Mitchell, Jane A

Ahmetaj-Shala, Blerina; Olanipekun, Michael; Tesfai, Abel; MacCallum, Niall; Kirkby, Nicholas S; Quinlan, Gregory J; Shih, Chih-Chin; Kawai, Ryota; Mumby, Sharon; Paul-Clark, Mark; Want, Elizabeth J; Mitchell, Jane A.

Affiliation

Ahmetaj-Shala B; Cardiothoracic Pharmacology, Vascular Biology, National Heart and Lung Institute, Imperial College London, London, SW3 6LY, United Kingdom. b.ahmetaj@imperial.ac.uk.
Olanipekun M; Department of Surgery and Cancer, Imperial College London, London, SW7 2BB, United Kingdom.
Tesfai A; Cardiothoracic Pharmacology, Vascular Biology, National Heart and Lung Institute, Imperial College London, London, SW3 6LY, United Kingdom.
MacCallum N; Critical Care, University College London Hospital, London, NW1 2BU, United Kingdom.
Kirkby NS; Cardiothoracic Pharmacology, Vascular Biology, National Heart and Lung Institute, Imperial College London, London, SW3 6LY, United Kingdom.
Quinlan GJ; Cardiothoracic Pharmacology, Vascular Biology, National Heart and Lung Institute, Imperial College London, London, SW3 6LY, United Kingdom.
Shih CC; Cardiothoracic Pharmacology, Vascular Biology, National Heart and Lung Institute, Imperial College London, London, SW3 6LY, United Kingdom.
Kawai R; Cardiothoracic Pharmacology, Vascular Biology, National Heart and Lung Institute, Imperial College London, London, SW3 6LY, United Kingdom.
Mumby S; Respiratory, Airway Disease, National Heart and Lung Institute, Imperial College London, London, SW3 6LY, United Kingdom.
Paul-Clark M; Cardiothoracic Pharmacology, Vascular Biology, National Heart and Lung Institute, Imperial College London, London, SW3 6LY, United Kingdom.
Want EJ; Department of Surgery and Cancer, Imperial College London, London, SW7 2BB, United Kingdom. e.want@imperial.ac.uk.
Mitchell JA; Cardiothoracic Pharmacology, Vascular Biology, National Heart and Lung Institute, Imperial College London, London, SW3 6LY, United Kingdom. j.a.mitchell@ic.ac.uk.

Sci Rep ; 8(1): 13987, 2018 09 18.

Article de En | MEDLINE | ID: mdl-30228360

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Arginine / Marqueurs biologiques / Chromatographie en phase liquide à haute performance / Syndrome de réponse inflammatoire généralisée / Spectrométrie de masse en tandem / Amines / Acides aminés Type d'étude: Prognostic_studies Limites: Aged / Female / Humans / Male Langue: En Journal: Sci Rep Année: 2018 Type de document: Article Pays d'affiliation: Royaume-Uni Pays de publication: Royaume-Uni

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