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Uptake and metabolism of mizoribine, an immunosuppressant, in L5178Y-R mouse lymphoma cells in vitro and peripheral blood mononuclear cells of rats and kidney transplant recipients in vivo.
Oda, Keisuke; Mori, Nobuhiro; Okumi, Masayoshi; Furusawa, Miyuki; Ishiguro, Masashi; Inoue, Kazuyuki; Shuto, Satoshi; Unagami, Kohei; Ishida, Hideki; Tanabe, Kazunari; Murakami, Teruo.
Affiliation
  • Oda K; Laboratory of Biopharmaceutics and Pharmacokinetics, Faculty of Pharmaceutical Sciences, Hiroshima International University, 5-1-1 Hiro-koshingai, Kure, Hiroshima 737-0112, Japan. Electronic address: oda@ps.hirokoku-u.ac.jp.
  • Mori N; Laboratory of Biopharmaceutics and Pharmacokinetics, Faculty of Pharmaceutical Sciences, Hiroshima International University, 5-1-1 Hiro-koshingai, Kure, Hiroshima 737-0112, Japan.
  • Okumi M; Department of Urology, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku, Tokyo 162-8666, Japan.
  • Furusawa M; Department of Urology, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku, Tokyo 162-8666, Japan.
  • Ishiguro M; Laboratory for Safety Assessment and ADME, Pharmaceuticals Research Center, Asahi Kasei Pharma Corporation, 632-1 Mifuku, Izunokunishi, Shizuoka 410-2321, Japan.
  • Inoue K; Medical Affairs Department, Pharmaceutical Business Administration Division, Asahi Kasei Pharma Corporation, 1-105 Kanda Jimbocho, Chiyoda-ku, Tokyo 101-8101, Japan.
  • Shuto S; Graduate School of Pharmaceutical Sciences, Hokkaido University, Kita-12, Nishi-6, Kita-ku, Sapporo 060-0812, Japan.
  • Unagami K; Department of Nephrology, Tokyo Women's Medical University, Yocho-machi Clinic, Yocho-machi 6-21, Shinjuku, Tokyo 162-0055, Japan.
  • Ishida H; Department of Urology, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku, Tokyo 162-8666, Japan.
  • Tanabe K; Department of Urology, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku, Tokyo 162-8666, Japan.
  • Murakami T; Laboratory of Biopharmaceutics and Pharmacokinetics, Faculty of Pharmaceutical Sciences, Hiroshima International University, 5-1-1 Hiro-koshingai, Kure, Hiroshima 737-0112, Japan.
Drug Metab Pharmacokinet ; 33(5): 232-239, 2018 Oct.
Article de En | MEDLINE | ID: mdl-30241694
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Ribonucléosides / Agranulocytes / Leucémie L5178 / Transplantation rénale / Immunosuppresseurs Limites: Animals Langue: En Journal: Drug Metab Pharmacokinet Sujet du journal: FARMACOLOGIA / METABOLISMO Année: 2018 Type de document: Article Pays de publication: Royaume-Uni
Texte intégral
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XML
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Ribonucléosides / Agranulocytes / Leucémie L5178 / Transplantation rénale / Immunosuppresseurs Limites: Animals Langue: En Journal: Drug Metab Pharmacokinet Sujet du journal: FARMACOLOGIA / METABOLISMO Année: 2018 Type de document: Article Pays de publication: Royaume-Uni