Paired Immunoglobulin-like Type 2 Receptor Alpha G78R variant alters ligand binding and confers protection to Alzheimer's disease.

Rathore, Nisha; Ramani, Sree Ranjani; Pantua, Homer; Payandeh, Jian; Bhangale, Tushar; Wuster, Arthur; Kapoor, Manav; Sun, Yonglian; Kapadia, Sharookh B; Gonzalez, Lino; Zarrin, Ali A; Goate, Alison; Hansen, David V; Behrens, Timothy W; Graham, Robert R

Rathore, Nisha; Ramani, Sree Ranjani; Pantua, Homer; Payandeh, Jian; Bhangale, Tushar; Wuster, Arthur; Kapoor, Manav; Sun, Yonglian; Kapadia, Sharookh B; Gonzalez, Lino; Zarrin, Ali A; Goate, Alison; Hansen, David V; Behrens, Timothy W; Graham, Robert R.

Affiliation

Rathore N; Department of OMNI Human Genetics, Genentech Inc., South San Francisco, California, United States of America.
Ramani SR; Department of Microchemistry, Proteomics & Lipidomics, Genentech Inc., South San Francisco, California, United States of America.
Pantua H; Department of Immunology and Infectious Diseases, Genentech Inc., South San Francisco, California, United States of America.
Payandeh J; Department of Structural Biology, Genentech Inc., South San Francisco, California, United States of America.
Bhangale T; Department of OMNI Human Genetics, Genentech Inc., South San Francisco, California, United States of America.
Wuster A; Department of Bioinformatics and Computational Biology, Genentech Inc., South San Francisco, California, United States of America.
Kapoor M; Department of OMNI Human Genetics, Genentech Inc., South San Francisco, California, United States of America.
Sun Y; Department of Bioinformatics and Computational Biology, Genentech Inc., South San Francisco, California, United States of America.
Kapadia SB; Department of Neuroscience, Ronald M. Loeb Center for Alzheimer's disease, Icahn School of Medicine at Mount Sinai, New York, United States of America.
Gonzalez L; Department of Immunology, Genentech Inc., South San Francisco, California, United States of America.
Zarrin AA; Department of Immunology and Infectious Diseases, Genentech Inc., South San Francisco, California, United States of America.
Goate A; Department of Proteomics & Biological Resources, Genentech Inc., South San Francisco, California, United States of America.
Hansen DV; Department of Immunology, Genentech Inc., South San Francisco, California, United States of America.
Behrens TW; Department of Neuroscience, Ronald M. Loeb Center for Alzheimer's disease, Icahn School of Medicine at Mount Sinai, New York, United States of America.
Graham RR; Department of Neuroscience, Genentech Inc., South San Francisco, California, United States of America.

PLoS Genet ; 14(11): e1007427, 2018 11.

Article de En | MEDLINE | ID: mdl-30388101

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Variation génétique / Glycoprotéines membranaires / Récepteurs immunologiques / Maladie d'Alzheimer Type d'étude: Prognostic_studies Limites: Animals / Humans Langue: En Journal: PLoS Genet Sujet du journal: GENETICA Année: 2018 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: États-Unis d'Amérique

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