Development of Pin1 Inhibitors and their Potential as Therapeutic Agents.

Nakatsu, Yusuke; Matsunaga, Yasuka; Ueda, Koji; Yamamotoya, Takeshi; Inoue, Yuki; Inoue, Masa-Ki; Mizuno, Yu; Kushiyama, Akifumi; Ono, Hiraku; Fujishiro, Midori; Ito, Hisanaka; Okabe, Takayoshi; Asano, Tomoichiro

Nakatsu, Yusuke; Matsunaga, Yasuka; Ueda, Koji; Yamamotoya, Takeshi; Inoue, Yuki; Inoue, Masa-Ki; Mizuno, Yu; Kushiyama, Akifumi; Ono, Hiraku; Fujishiro, Midori; Ito, Hisanaka; Okabe, Takayoshi; Asano, Tomoichiro.

Affiliation

Nakatsu Y; Department of Medical Science, Graduate School of Medicine, Hiroshima University, Hiroshima City, Hiroshima 734-8553, Japan.
Matsunaga Y; Department of Medical Science, Graduate School of Medicine, Hiroshima University, Hiroshima City, Hiroshima 734-8553, Japan.
Ueda K; Department of Medical Science, Graduate School of Medicine, Hiroshima University, Hiroshima City, Hiroshima 734-8553, Japan.
Yamamotoya T; Department of Medical Science, Graduate School of Medicine, Hiroshima University, Hiroshima City, Hiroshima 734-8553, Japan.
Inoue Y; Department of Medical Science, Graduate School of Medicine, Hiroshima University, Hiroshima City, Hiroshima 734-8553, Japan.
Inoue MK; Department of Medical Science, Graduate School of Medicine, Hiroshima University, Hiroshima City, Hiroshima 734-8553, Japan.
Mizuno Y; Department of Medical Science, Graduate School of Medicine, Hiroshima University, Hiroshima City, Hiroshima 734-8553, Japan.
Kushiyama A; The Division of Diabetes and Metabolism, Institute for Adult Diseases, Asahi Life Foundation, Chuo-ku, Tokyo 103-0002, Japan.
Ono H; Department of Clinical Cell Biology, Chiba University Graduate School of Medicine, Chiba City, Chiba 260-8677, Japan.
Fujishiro M; The Division of Diabetes and Metabolic Diseases, Nihon University School of Medicine, Itabashi, Tokyo 173-8610, Japan.
Ito H; School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan.
Okabe T; Drug Discovery Initiative, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
Asano T; Department of Medical Science, Graduate School of Medicine, Hiroshima University, Hiroshima City, Hiroshima 734-8553, Japan.

Curr Med Chem ; 27(20): 3314-3329, 2020.

Article de En | MEDLINE | ID: mdl-30394205

Sujet(s)
Mots clés

ATRA; Pin1 inhibitors; Prolyl isomerase Pin1; cancer; fibrosis; juglone; metabolic syndromes.

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: NIMA-interacting peptidylprolyl isomerase Limites: Animals / Humans Langue: En Journal: Curr Med Chem Sujet du journal: QUIMICA Année: 2020 Type de document: Article Pays d'affiliation: Japon Pays de publication: Émirats arabes unis

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