Different structures of berberine and five other protoberberine alkaloids that affect P-glycoprotein-mediated efflux capacity.

Zhang, Yi-Ting; Yu, Yu-Qi; Yan, Xiao-Xia; Wang, Wen-Jie; Tian, Xiao-Ting; Wang, Le; Zhu, Wei-Liang; Gong, Li-Kun; Pan, Guo-Yu

Zhang, Yi-Ting; Yu, Yu-Qi; Yan, Xiao-Xia; Wang, Wen-Jie; Tian, Xiao-Ting; Wang, Le; Zhu, Wei-Liang; Gong, Li-Kun; Pan, Guo-Yu.

Affiliation

Zhang YT; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
Yu YQ; University of Chinese Academy of Sciences, Beijing, 100049, China.
Yan XX; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
Wang WJ; University of Chinese Academy of Sciences, Beijing, 100049, China.
Tian XT; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
Wang L; University of Chinese Academy of Sciences, Beijing, 100049, China.
Zhu WL; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
Gong LK; University of Chinese Academy of Sciences, Beijing, 100049, China.
Pan GY; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.

Acta Pharmacol Sin ; 40(1): 133-142, 2019 Jan.

Article de En | MEDLINE | ID: mdl-30442987

Sujet(s)
Mots clés

P-glycoprotein; berberine; binding affinity; efflux; protoberberine alkaloid

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Berbérine / Sous-famille B de transporteurs à cassette liant l'ATP Limites: Animals / Humans / Male Langue: En Journal: Acta Pharmacol Sin Sujet du journal: FARMACOLOGIA Année: 2019 Type de document: Article Pays d'affiliation: Chine

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