Visual detection of cancer cells by using in situ grown functional Cu2-xSe/reduced graphene oxide hybrids acting as an efficient nanozyme.
Analyst
; 144(2): 716-721, 2019 Jan 21.
Article
de En
| MEDLINE
| ID: mdl-30520465
ABSTRACT
A simple protocol for in situ growth of Cu2-xSe nanoparticles on graphene oxide hybrids (Cu2-xSe/rGO) acting as an efficient nanozyme is developed and thus a sensitive visual detection method of cancer cells is proposed. The Cu2-xSe/rGO heterogeneous nanomaterials have been proven to exhibit high peroxidase-like activity to catalyze the reaction of the peroxidase substrate in the presence of hydrogen peroxide. Herein, we used Cu2-xSe/rGO as a signal transducer to develop a colorimetric assay for the direct detection of cancer cells and a total of 63 cancer cells (MCF-7) can be distinguished by naked-eye observation. The results showed that the Cu2-xSe/rGO hybrids could be the promising nanozyme mimetics for potential applications in bioanalytical fields.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Oxydes
/
Sélénium
/
Colorimétrie
/
Cuivre
/
Matériaux biomimétiques
/
Nanostructures
/
Graphite
Type d'étude:
Diagnostic_studies
Limites:
Humans
Langue:
En
Journal:
Analyst
Année:
2019
Type de document:
Article