Pattern of urine iodine excretion with low iodine diet during preparation for radioactive iodine ablation in patients with thyroid cancer.
Head Neck
; 41(2): 381-387, 2019 02.
Article
de En
| MEDLINE
| ID: mdl-30548084
ABSTRACT
BACKGROUND:
The optimal period of low iodine diet during preparation for radioactive iodine (RAI) ablation in an area with iodine-rich diet was investigated.METHODS:
Ninety-four patients with thyroid cancer who underwent low iodine diet and RAI were prospectively allocated into 2 groups-thyroxine withdrawal or using recombinant human thyroid stimulating hormone (rhTSH) for TSH stimulation. Their urinary iodine excretion (UIE) patterns were analyzed.RESULTS:
There was no clinicopathological difference between the 2 groups except for tumor size and lymph node status. The UIE (median iodine to creatinine ratio, I/Cr) in the withdrawal group on the 7th and 14th day were 18.3 and 17.9 µg/gCr, respectively, with adequate preparation rate of 93.3% on both days (cutoff value 100 µg/gCr). In the rhTSH group, the median I/Cr on the 7th and 14th day were 48.0 and 45.7 µg/gCr (adequate preparation rates 91.8% and 93.8%), respectively.CONCLUSION:
One week of low iodine diet is sufficient preparation for RAI regardless of method of TSH stimulation.Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Tumeurs de la thyroïde
/
Carcinomes
/
Fer alimentaire
/
Régime alimentaire
/
Techniques d'ablation
/
Iode
Limites:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Langue:
En
Journal:
Head Neck
Sujet du journal:
NEOPLASIAS
Année:
2019
Type de document:
Article
Pays d'affiliation:
Corée du Sud