Exendin-4 prevented pancreatic beta cells from apoptosis in (Type I) diabetic mouse via keap1-Nrf2 signaling.

He, Jinshui; Zhang, Xu; Lian, Chaowei; Wu, Jinzhi; Fang, Yanling; Ye, Xiaoling

He, Jinshui; Zhang, Xu; Lian, Chaowei; Wu, Jinzhi; Fang, Yanling; Ye, Xiaoling.

Affiliation

He J; 1 Department of Pediatrics, Affiliated Hospital of Zhangzhou, Fujian Medical University, Zhangzhou 363000, China.
Zhang X; 1 Department of Pediatrics, Affiliated Hospital of Zhangzhou, Fujian Medical University, Zhangzhou 363000, China.
Lian C; 1 Department of Pediatrics, Affiliated Hospital of Zhangzhou, Fujian Medical University, Zhangzhou 363000, China.
Wu J; 2 Department of endocrinology, Affiliated Hospital of Zhangzhou, Fujian Medical University, Zhangzhou 363000, China.
Fang Y; 1 Department of Pediatrics, Affiliated Hospital of Zhangzhou, Fujian Medical University, Zhangzhou 363000, China.
Ye X; 1 Department of Pediatrics, Affiliated Hospital of Zhangzhou, Fujian Medical University, Zhangzhou 363000, China.

Exp Biol Med (Maywood) ; 244(1): 28-35, 2019 01.

Article de En | MEDLINE | ID: mdl-30638057

Sujet(s)
Mots clés

IDM; Keap1-Nrf2-ARE; PKC; ROS; apoptosis; exendin-4

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Diabète de type 1 / Facteur-2 apparenté à NF-E2 / Protéine-1 de type kelch associée à ECH / Exénatide Limites: Animals Langue: En Journal: Exp Biol Med (Maywood) Sujet du journal: BIOLOGIA / FISIOLOGIA / MEDICINA Année: 2019 Type de document: Article Pays d'affiliation: Chine Pays de publication: Royaume-Uni

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