Behavioral flexibility in a mouse model for obsessive-compulsive disorder: Impaired Pavlovian reversal learning in SAPAP3 mutants.

van den Boom, Bastijn J G; Mooij, Adriana H; Miseviciute, Ieva; Denys, Damiaan; Willuhn, Ingo

van den Boom, Bastijn J G; Mooij, Adriana H; Miseviciute, Ieva; Denys, Damiaan; Willuhn, Ingo.

Affiliation

van den Boom BJG; Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences, Amsterdam, The Netherlands.
Mooij AH; Department of Psychiatry, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Miseviciute I; Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences, Amsterdam, The Netherlands.
Denys D; Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences, Amsterdam, The Netherlands.
Willuhn I; Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences, Amsterdam, The Netherlands.

Genes Brain Behav ; 18(4): e12557, 2019 04.

Article de En | MEDLINE | ID: mdl-30688005

Sujet(s)
Mots clés

Pavlovian conditioning; SAPAP3 mutant mice; anxiety; behavioral flexibility; cognitive flexibility; compulsive behavior; general activity; obsessive-compulsive disorder; reversal learning; symptoms relationship

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Conditionnement classique / Protéines de tissu nerveux / Trouble obsessionnel compulsif Type d'étude: Prognostic_studies Limites: Animals Langue: En Journal: Genes Brain Behav Sujet du journal: CIENCIAS DO COMPORTAMENTO / GENETICA Année: 2019 Type de document: Article Pays d'affiliation: Pays-Bas

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