Your browser doesn't support javascript.
loading
Prevention of schizophrenia deficits via non-invasive adolescent frontal cortex stimulation in rats.
Hadar, Ravit; Winter, Rebecca; Edemann-Callesen, Henriette; Wieske, Franziska; Habelt, Bettina; Khadka, Niranjan; Felgel-Farnholz, Viktoria; Barroeta-Hlusicka, Elizabeth; Reis, Janine; Tatarau, Cristian Alexandru; Funke, Klaus; Fritsch, Brita; Bernhardt, Nadine; Bikson, Marom; Nitsche, Michael A; Winter, Christine.
Affiliation
  • Hadar R; Department of Psychiatry and Psychotherapy, Charité University Medicine Berlin, Campus Mitte, Berlin, Germany.
  • Winter R; Department of Psychiatry and Psychotherapy, Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
  • Edemann-Callesen H; Department of Psychiatry and Psychotherapy, Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
  • Wieske F; Department of Psychiatry and Psychotherapy, Charité University Medicine Berlin, Campus Mitte, Berlin, Germany.
  • Habelt B; Department of Psychiatry and Psychotherapy, Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
  • Khadka N; International Graduate Program Medical Neurosciences, Charité Universitätsmedizin Berlin, Berlin, Germany.
  • Felgel-Farnholz V; Department of Psychiatry and Psychotherapy, Charité University Medicine Berlin, Campus Mitte, Berlin, Germany.
  • Barroeta-Hlusicka E; Department of Psychiatry and Psychotherapy, Charité University Medicine Berlin, Campus Mitte, Berlin, Germany.
  • Reis J; Department of Psychiatry and Psychotherapy, Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
  • Tatarau CA; Department of Biomedical Engineering, The City College of New York, CUNY, New York, NY, 10031, USA.
  • Funke K; Department of Psychiatry and Psychotherapy, Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
  • Fritsch B; Department of Psychiatry and Psychotherapy, Charité University Medicine Berlin, Campus Mitte, Berlin, Germany.
  • Bernhardt N; Department of Psychiatry and Psychotherapy, Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
  • Bikson M; Department of Neurology, University Medical Center, Albert Ludwigs University Freiburg, Freiburg, Germany.
  • Nitsche MA; Department of Psychiatry and Psychotherapy, Charité University Medicine Berlin, Campus Mitte, Berlin, Germany.
  • Winter C; Department of Neurophysiology, Medical School of the Ruhr-Universität Bochum, Bochum, Germany.
Mol Psychiatry ; 25(4): 896-905, 2020 04.
Article de En | MEDLINE | ID: mdl-30692610
ABSTRACT
Schizophrenia is a severe neurodevelopmental psychiatric affliction manifested behaviorally at late adolescence/early adulthood. Current treatments comprise antipsychotics which act solely symptomatic, are limited in their effectiveness and often associated with side-effects. We here report that application of non-invasive transcranial direct current stimulation (tDCS) during adolescence, prior to schizophrenia-relevant behavioral manifestation, prevents the development of positive symptoms and related neurobiological alterations in the maternal immune stimulation (MIS) model of schizophrenia.
Sujet(s)
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Schizophrénie / Lobe frontal Limites: Animals Langue: En Journal: Mol Psychiatry Sujet du journal: BIOLOGIA MOLECULAR / PSIQUIATRIA Année: 2020 Type de document: Article Pays d'affiliation: Allemagne
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Schizophrénie / Lobe frontal Limites: Animals Langue: En Journal: Mol Psychiatry Sujet du journal: BIOLOGIA MOLECULAR / PSIQUIATRIA Année: 2020 Type de document: Article Pays d'affiliation: Allemagne