Application of a quality-by-design approach for utilizing sodium stearyl fumarate as a taste-masking agent in dextromethorphan hydrobromide orally disintegrating tablets.

Mahrous, Gamal Mohamed; Ibrahim, Mohamed Abbas; Mostafa, Haitham Fady; Elzayat, Ehab Mostafa

Mahrous, Gamal Mohamed; Ibrahim, Mohamed Abbas; Mostafa, Haitham Fady; Elzayat, Ehab Mostafa.

Affiliation

Mahrous GM; a Department of Pharmaceutics , College of Pharmacy, King Saud University , Riyadh , Kingdom of Saudi Arabia.
Ibrahim MA; a Department of Pharmaceutics , College of Pharmacy, King Saud University , Riyadh , Kingdom of Saudi Arabia.
Mostafa HF; b Department of Pharmaceutics and Industrial Pharmacy , College of Pharmacy, Al Azhar University , Assiut , Egypt.
Elzayat EM; a Department of Pharmaceutics , College of Pharmacy, King Saud University , Riyadh , Kingdom of Saudi Arabia.

Pharm Dev Technol ; 24(6): 711-719, 2019 Jul.

Article de En | MEDLINE | ID: mdl-30714850

Sujet(s)
Mots clés

Orally disintegrating tablets; dextromethorphan HBr; quality by design; sodium stearyl fumarate; taste-masking

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Antitussifs / Dextrométhorphane / Excipients / Fumarates Type d'étude: Clinical_trials Langue: En Journal: Pharm Dev Technol Sujet du journal: FARMACIA Année: 2019 Type de document: Article Pays de publication: Royaume-Uni

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