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Defining the impact of mutation accumulation on replicative lifespan in yeast using cancer-associated mutator phenotypes.
Lee, Mitchell B; Dowsett, Ian T; Carr, Daniel T; Wasko, Brian M; Stanton, Sarah G; Chung, Michael S; Ghodsian, Niloufar; Bode, Anna; Kiflezghi, Michael G; Uppal, Priya A; Grayden, Katherine A; Elala, Yordanos C; Tang, Thao T; Tran, Ngoc H B; Tran, Thu H B; Diep, Anh B; Hope, Michael; Promislow, Daniel E L; Kennedy, Scott R; Kaeberlein, Matt; Herr, Alan J.
Affiliation
  • Lee MB; Department of Pathology, University of Washington, Seattle, WA 98195-7705.
  • Dowsett IT; Department of Pathology, University of Washington, Seattle, WA 98195-7705.
  • Carr DT; Molecular Medicine and Mechanisms of Disease Program, University of Washington, Seattle, WA 98195-7705.
  • Wasko BM; Department of Pathology, University of Washington, Seattle, WA 98195-7705.
  • Stanton SG; Department of Pathology, University of Washington, Seattle, WA 98195-7705.
  • Chung MS; Department of Biology and Biotechnology, University of Houston-Clear Lake, Houston, TX 77058.
  • Ghodsian N; Department of Pathology, University of Washington, Seattle, WA 98195-7705.
  • Bode A; Department of Pathology, University of Washington, Seattle, WA 98195-7705.
  • Kiflezghi MG; Department of Pathology, University of Washington, Seattle, WA 98195-7705.
  • Uppal PA; Department of Pathology, University of Washington, Seattle, WA 98195-7705.
  • Grayden KA; Department of Pathology, University of Washington, Seattle, WA 98195-7705.
  • Elala YC; Molecular Medicine and Mechanisms of Disease Program, University of Washington, Seattle, WA 98195-7705.
  • Tang TT; Department of Pathology, University of Washington, Seattle, WA 98195-7705.
  • Tran NHB; Department of Pathology, University of Washington, Seattle, WA 98195-7705.
  • Tran THB; Department of Pathology, University of Washington, Seattle, WA 98195-7705.
  • Diep AB; Department of Pathology, University of Washington, Seattle, WA 98195-7705.
  • Hope M; Department of Pathology, University of Washington, Seattle, WA 98195-7705.
  • Promislow DEL; Department of Pathology, University of Washington, Seattle, WA 98195-7705.
  • Kennedy SR; Department of Pathology, University of Washington, Seattle, WA 98195-7705.
  • Kaeberlein M; Department of Pathology, University of Washington, Seattle, WA 98195-7705.
  • Herr AJ; Department of Pathology, University of Washington, Seattle, WA 98195-7705.
Proc Natl Acad Sci U S A ; 116(8): 3062-3071, 2019 02 19.
Article de En | MEDLINE | ID: mdl-30718408

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Vieillissement / Réparation de l'ADN / Longévité / Tumeurs Type d'étude: Prognostic_studies / Risk_factors_studies Limites: Humans Langue: En Journal: Proc Natl Acad Sci U S A Année: 2019 Type de document: Article Pays de publication: États-Unis d'Amérique

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Vieillissement / Réparation de l'ADN / Longévité / Tumeurs Type d'étude: Prognostic_studies / Risk_factors_studies Limites: Humans Langue: En Journal: Proc Natl Acad Sci U S A Année: 2019 Type de document: Article Pays de publication: États-Unis d'Amérique