[Adherence to chronic polytherapy in secondary prevention of myocardial infarction: limits and perspectives.] / Aderenza alla politerapia cronica nella prevenzione secondaria dell'infarto: limiti e prospettive.
Recenti Prog Med
; 110(1): 7-9, 2019 Jan.
Article
de It
| MEDLINE
| ID: mdl-30720011
ABSTRACT
Patients who have had an acute myocardial infarction (MI) are at increased risk of mortality and morbidity. International guidelines agree on the use of combination of the following drugs platelet antiplatelets, ß-blockers, ACEI/ARBs and statins. The benefits of chronic polytherapy in reducing cardiovascular disease have been clearly shown. However, observational studies reported poor adherence to chronic polytherapy. We identified about 52,000 patients discharged from hospital with a first MI diagnosis from three Italian regions Lazio, Toscana and Sicilia. Adherence to chronic poly-therapy in the two years after hospital discharge ranged from 63% in the Lazio region to 27% in the Sicilia region. More than 75 percent of MI patients had chronic concomitant diseases. Chronic diseases played a major role among barriers to adherence. MI patients with multimorbidity have complex health needs but, due to the current traditional disease-oriented approach, they face a highly fragmented form of care that leads to incomplete, inefficient, ineffective and possibly harmful clinical interventions, and are likely to receive complex drug regimens, which increase the risk of inappropriate prescribing, drug-drug interactions, and poor adherence. In order to address patient-specific needs, a network of multidisciplinary teams should be implemented, avoiding fragmentation and ensuring continuity of care.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Guides de bonnes pratiques cliniques comme sujet
/
Adhésion au traitement médicamenteux
/
Infarctus du myocarde
Type d'étude:
Guideline
/
Observational_studies
/
Prognostic_studies
Limites:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Pays/Région comme sujet:
Europa
Langue:
It
Journal:
Recenti Prog Med
Année:
2019
Type de document:
Article