Neoadjuvant nivolumab modifies the tumor immune microenvironment in resectable glioblastoma.

Schalper, Kurt A; Rodriguez-Ruiz, Maria E; Diez-Valle, Ricardo; López-Janeiro, Alvaro; Porciuncula, Angelo; Idoate, Miguel A; Inogés, Susana; de Andrea, Carlos; López-Diaz de Cerio, Ascensión; Tejada, Sonia; Berraondo, Pedro; Villarroel-Espindola, Franz; Choi, Jungmin; Gúrpide, Alfonso; Giraldez, Miriam; Goicoechea, Iosune; Gallego Perez-Larraya, Jaime; Sanmamed, Miguel F; Perez-Gracia, Jose L; Melero, Ignacio

Schalper, Kurt A; Rodriguez-Ruiz, Maria E; Diez-Valle, Ricardo; López-Janeiro, Alvaro; Porciuncula, Angelo; Idoate, Miguel A; Inogés, Susana; de Andrea, Carlos; López-Diaz de Cerio, Ascensión; Tejada, Sonia; Berraondo, Pedro; Villarroel-Espindola, Franz; Choi, Jungmin; Gúrpide, Alfonso; Giraldez, Miriam; Goicoechea, Iosune; Gallego Perez-Larraya, Jaime; Sanmamed, Miguel F; Perez-Gracia, Jose L; Melero, Ignacio.

Affiliation

Schalper KA; Department of Pathology, Yale School of Medicine, New Haven, CT, USA.
Rodriguez-Ruiz ME; Department of Oncology, Clínica Universidad de Navarra, Pamplona, Spain.
Diez-Valle R; Centro de Investigación Biomedica en Red de Oncología (CIBERONC), Madrid, Spain.
López-Janeiro A; Instituto de Investigación Sanitaria de Navarra (IDISNA), Pamplona, Spain.
Porciuncula A; Department of Neurosurgery, Clínica Universidad de Navarra, Pamplona, Spain.
Idoate MA; Department of Immunology, Clínica Universidad de Navarra, Pamplona, Spain.
Inogés S; Department of Pathology, Clínica Universidad de Navarra, Pamplona, Spain.
de Andrea C; Department of Pathology, Yale School of Medicine, New Haven, CT, USA.
López-Diaz de Cerio A; Department of Pathology, Clínica Universidad de Navarra, Pamplona, Spain.
Tejada S; Department of Immunology, Clínica Universidad de Navarra, Pamplona, Spain.
Berraondo P; Department of Pathology, Clínica Universidad de Navarra, Pamplona, Spain.
Villarroel-Espindola F; Department of Immunology, Clínica Universidad de Navarra, Pamplona, Spain.
Choi J; Department of Neurosurgery, Clínica Universidad de Navarra, Pamplona, Spain.
Gúrpide A; Centro de Investigación Medica Aplicada (CIMA), Universidad de Navarra, Pamplona, Spain.
Giraldez M; Department of Pathology, Yale School of Medicine, New Haven, CT, USA.
Goicoechea I; Department of Genetics, Yale School of Medicine, New Haven, CT, USA.
Gallego Perez-Larraya J; Department of Oncology, Clínica Universidad de Navarra, Pamplona, Spain.
Sanmamed MF; Department of Pharmacy, Clínica Universidad de Navarra, Pamplona, Spain.
Perez-Gracia JL; Department of Oncology, Clínica Universidad de Navarra, Pamplona, Spain.
Melero I; Department of Neurology, Clínica Universidad de Navarra, Pamplona, Spain.

Nat Med ; 25(3): 470-476, 2019 03.

Article de En | MEDLINE | ID: mdl-30742120

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Tumeurs du cerveau / Lymphocytes TIL / Glioblastome / Procédures de neurochirurgie / Traitement néoadjuvant / Microenvironnement tumoral / Antinéoplasiques immunologiques / Nivolumab Limites: Adult / Aged / Female / Humans / Male / Middle aged Langue: En Journal: Nat Med Sujet du journal: BIOLOGIA MOLECULAR / MEDICINA Année: 2019 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: États-Unis d'Amérique

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