Postoperative hyperglycemia in patients undergoing cytoreductive surgery and HIPEC: A cohort study.
Int J Surg
; 64: 5-9, 2019 Apr.
Article
de En
| MEDLINE
| ID: mdl-30772524
ABSTRACT
BACKGROUND:
Hyperglycemia following elective or emergency surgery is generally associated with an increased risk of complications. The impact of hyperglycemia following surgery for peritoneal surface malignancy remains unclear. MATERIALS ANDMETHODS:
Records of patients undergoing cytoreduction and HIPEC for peritoneal surface malignancy were reviewed at two institutions. Postoperative hyperglycemia was defined as serum glucose >140â¯mg/dl at the first measurement after surgery. Lengths of stay and 30-day complication rates were recorded.RESULTS:
There were 115 total patients included, 65 from Institution A (A) and 50 from Institution B (B). Perioperative steroids were given to 55% (A) and 100% (B) of patients, with postoperative hyperglycemia present in 39% and 86% of patients respectively. Complication rates were not significantly different in patients with hyperglycemia versus patients who were normoglycemic at each site [56% vs. 53%, pâ¯=â¯0.8â¯at (A); 47% vs. 43%, pâ¯=â¯1.0â¯at (B)]. Infection rates were also similar between groups [16% vs. 13%, pâ¯=â¯0.72â¯at (A); 14% vs. 29%, pâ¯=â¯0.31â¯at (B)].CONCLUSIONS:
Rates of hyperglycemia in patients undergoing cytoreduction and HIPEC are high. This likely represents a stress response but does not seem to have the same adverse impact as seen in other abdominal surgical patient populations.Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Tumeurs du péritoine
/
Complications postopératoires
/
Interventions chirurgicales de cytoréduction
/
Hyperglycémie
/
Hyperthermie provoquée
Type d'étude:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Risk_factors_studies
Limites:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Langue:
En
Journal:
Int J Surg
Année:
2019
Type de document:
Article
Pays d'affiliation:
États-Unis d'Amérique