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Synthesis, structure-activity relationship studies and biological characterization of new [1,2,4]triazolo[1,5-a]pyrimidine-based LSD1/KDM1A inhibitors.
Wang, Shuai; Li, Zhong-Rui; Suo, Feng-Zhi; Yuan, Xiao-Han; Yu, Bin; Liu, Hong-Min.
Affiliation
  • Wang S; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, 450001, China; Key Laboratory of Advanced Drug Preparation Technologies (Ministry of Education), Zhengzhou University, Zhengzhou, 450001, China; Co-Innovation Center of Henan Province for New Drug R & D and Preclinical Safety, Z
  • Li ZR; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, 450001, China; Key Laboratory of Advanced Drug Preparation Technologies (Ministry of Education), Zhengzhou University, Zhengzhou, 450001, China; Co-Innovation Center of Henan Province for New Drug R & D and Preclinical Safety, Z
  • Suo FZ; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, 450001, China; Key Laboratory of Advanced Drug Preparation Technologies (Ministry of Education), Zhengzhou University, Zhengzhou, 450001, China; Co-Innovation Center of Henan Province for New Drug R & D and Preclinical Safety, Z
  • Yuan XH; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, 450001, China; Key Laboratory of Advanced Drug Preparation Technologies (Ministry of Education), Zhengzhou University, Zhengzhou, 450001, China; Co-Innovation Center of Henan Province for New Drug R & D and Preclinical Safety, Z
  • Yu B; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, 450001, China; State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, 210023, Jiangsu, China; Key Laboratory of Advanced Drug Preparation Technologies (Ministry of Education), Zhengzhou University, Zhengz
  • Liu HM; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, 450001, China; Key Laboratory of Advanced Drug Preparation Technologies (Ministry of Education), Zhengzhou University, Zhengzhou, 450001, China; Co-Innovation Center of Henan Province for New Drug R & D and Preclinical Safety, Z
Eur J Med Chem ; 167: 388-401, 2019 Apr 01.
Article de En | MEDLINE | ID: mdl-30780087
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Pyrimidines / Triazoles / Conception de médicament / Antienzymes / Histone Demethylases Type d'étude: Prognostic_studies Limites: Humans Langue: En Journal: Eur J Med Chem Année: 2019 Type de document: Article Pays de publication: France
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Pyrimidines / Triazoles / Conception de médicament / Antienzymes / Histone Demethylases Type d'étude: Prognostic_studies Limites: Humans Langue: En Journal: Eur J Med Chem Année: 2019 Type de document: Article Pays de publication: France