Discovery of Imidazo[1,2-<i>a</i>]pyrazines and Pyrazolo[1,5-<i>c</i>]pyrimidines as TARP Î³-8 Selective AMPAR Negative Modulators.

Savall, Brad M; Wu, Dongpei; Swanson, Devin M; Seierstad, Mark; Wu, Nyantsz; Vives Martinez, Jorge; García Olmos, Beatriz; Lord, Brian; Coe, Kevin; Koudriakova, Tatiana; Lovenberg, Timothy W; Carruthers, Nicholas I; Maher, Michael P; Ameriks, Michael K

Discovery of Imidazo[1,2-a]pyrazines and Pyrazolo[1,5-c]pyrimidines as TARP Î³-8 Selective AMPAR Negative Modulators.

Savall, Brad M; Wu, Dongpei; Swanson, Devin M; Seierstad, Mark; Wu, Nyantsz; Vives Martinez, Jorge; García Olmos, Beatriz; Lord, Brian; Coe, Kevin; Koudriakova, Tatiana; Lovenberg, Timothy W; Carruthers, Nicholas I; Maher, Michael P; Ameriks, Michael K.

Affiliation

Savall BM; Sanford Burnham Prebys Medical Discovery Institute, 10901 N. Torrey Pines Road, La Jolla, California 92037, United States.
Wu D; Janssen Research & Development L.L.C., 3210 Merryfield Row, San Diego, California 92121 United States.
Swanson DM; Janssen Research & Development L.L.C., 3210 Merryfield Row, San Diego, California 92121 United States.
Seierstad M; Janssen Research & Development L.L.C., 3210 Merryfield Row, San Diego, California 92121 United States.
Wu N; Janssen Research & Development L.L.C., 3210 Merryfield Row, San Diego, California 92121 United States.
Vives Martinez J; Eurofins-Villapharma Research S.L., Parque Tecnológico de Fuente Alamo, Carretera El Estrecho-Lobosilo, Km. 2,5, E-30320 Fuente Alamo (Murcia), Spain.
García Olmos B; Eurofins-Villapharma Research S.L., Parque Tecnológico de Fuente Alamo, Carretera El Estrecho-Lobosilo, Km. 2,5, E-30320 Fuente Alamo (Murcia), Spain.
Lord B; Janssen Research & Development L.L.C., 3210 Merryfield Row, San Diego, California 92121 United States.
Coe K; Janssen Research & Development L.L.C., 3210 Merryfield Row, San Diego, California 92121 United States.
Koudriakova T; Janssen Research & Development L.L.C., 3210 Merryfield Row, San Diego, California 92121 United States.
Lovenberg TW; Janssen Research & Development L.L.C., 3210 Merryfield Row, San Diego, California 92121 United States.
Carruthers NI; Janssen Research & Development L.L.C., 3210 Merryfield Row, San Diego, California 92121 United States.
Maher MP; Janssen Research & Development L.L.C., 3210 Merryfield Row, San Diego, California 92121 United States.
Ameriks MK; Janssen Research & Development L.L.C., 3210 Merryfield Row, San Diego, California 92121 United States.

ACS Med Chem Lett ; 10(3): 267-272, 2019 Mar 14.

Article de En | MEDLINE | ID: mdl-30891124

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Langue: En Journal: ACS Med Chem Lett Année: 2019 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: États-Unis d'Amérique

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