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Metagenomic analysis of colorectal cancer datasets identifies cross-cohort microbial diagnostic signatures and a link with choline degradation.
Thomas, Andrew Maltez; Manghi, Paolo; Asnicar, Francesco; Pasolli, Edoardo; Armanini, Federica; Zolfo, Moreno; Beghini, Francesco; Manara, Serena; Karcher, Nicolai; Pozzi, Chiara; Gandini, Sara; Serrano, Davide; Tarallo, Sonia; Francavilla, Antonio; Gallo, Gaetano; Trompetto, Mario; Ferrero, Giulio; Mizutani, Sayaka; Shiroma, Hirotsugu; Shiba, Satoshi; Shibata, Tatsuhiro; Yachida, Shinichi; Yamada, Takuji; Wirbel, Jakob; Schrotz-King, Petra; Ulrich, Cornelia M; Brenner, Hermann; Arumugam, Manimozhiyan; Bork, Peer; Zeller, Georg; Cordero, Francesca; Dias-Neto, Emmanuel; Setubal, João Carlos; Tett, Adrian; Pardini, Barbara; Rescigno, Maria; Waldron, Levi; Naccarati, Alessio; Segata, Nicola.
Affiliation
  • Thomas AM; Department CIBIO, University of Trento, Trento, Italy.
  • Manghi P; Biochemistry Department, Chemistry Institute, University of São Paulo, São Paulo, Brazil.
  • Asnicar F; Medical Genomics Laboratory, CIPE/A.C. Camargo Cancer Center, São Paulo, Brazil.
  • Pasolli E; Department CIBIO, University of Trento, Trento, Italy.
  • Armanini F; Department CIBIO, University of Trento, Trento, Italy.
  • Zolfo M; Department CIBIO, University of Trento, Trento, Italy.
  • Beghini F; Department CIBIO, University of Trento, Trento, Italy.
  • Manara S; Department CIBIO, University of Trento, Trento, Italy.
  • Karcher N; Department CIBIO, University of Trento, Trento, Italy.
  • Pozzi C; Department CIBIO, University of Trento, Trento, Italy.
  • Gandini S; Department CIBIO, University of Trento, Trento, Italy.
  • Serrano D; IEO, European Institute of Oncology IRCCS, Milan, Italy.
  • Tarallo S; IEO, European Institute of Oncology IRCCS, Milan, Italy.
  • Francavilla A; IEO, European Institute of Oncology IRCCS, Milan, Italy.
  • Gallo G; Italian Institute for Genomic Medicine, Turin, Italy.
  • Trompetto M; Italian Institute for Genomic Medicine, Turin, Italy.
  • Ferrero G; Department of Surgical and Medical Sciences, University of Catanzaro, Catanzaro, Italy.
  • Mizutani S; Department of Colorectal Surgery, Clinica S. Rita, Vercelli, Italy.
  • Shiroma H; Department of Colorectal Surgery, Clinica S. Rita, Vercelli, Italy.
  • Shiba S; Department of Computer Science, University of Turin, Turin, Italy.
  • Shibata T; School of Life Science and Technology, Tokyo Institute of Technology, Tokyo, Japan.
  • Yachida S; Research Fellow of Japan Society for the Promotion of Science, Tokyo, Japan.
  • Yamada T; School of Life Science and Technology, Tokyo Institute of Technology, Tokyo, Japan.
  • Wirbel J; Division of Cancer Genomics, National Cancer Center Research Institute, Tokyo, Japan.
  • Schrotz-King P; Division of Cancer Genomics, National Cancer Center Research Institute, Tokyo, Japan.
  • Ulrich CM; Human Genome Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
  • Brenner H; Division of Cancer Genomics, National Cancer Center Research Institute, Tokyo, Japan.
  • Arumugam M; Department of Cancer Genome Informatics, Osaka University, Osaka, Japan.
  • Bork P; School of Life Science and Technology, Tokyo Institute of Technology, Tokyo, Japan.
  • Zeller G; PRESTO, Japan Science and Technology Agency, Saitama, Japan.
  • Cordero F; Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.
  • Dias-Neto E; Division of Preventive Oncology, National Center for Tumor Diseases and German Cancer Research Center, Heidelberg, Germany.
  • Setubal JC; Huntsman Cancer Institute and Department of Population Health Sciences, University of Utah, Salt Lake City, UT, USA.
  • Tett A; Division of Preventive Oncology, National Center for Tumor Diseases and German Cancer Research Center, Heidelberg, Germany.
  • Pardini B; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany.
  • Rescigno M; German Cancer Consortium, German Cancer Research Center, Heidelberg, Germany.
  • Waldron L; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Naccarati A; Faculty of Healthy Sciences, University of Southern Denmark, Odense, Denmark.
  • Segata N; Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.
Nat Med ; 25(4): 667-678, 2019 04.
Article de En | MEDLINE | ID: mdl-30936548
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Tumeurs colorectales / Choline / Métagénomique Type d'étude: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limites: Humans Langue: En Journal: Nat Med Sujet du journal: BIOLOGIA MOLECULAR / MEDICINA Année: 2019 Type de document: Article Pays d'affiliation: Italie
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Tumeurs colorectales / Choline / Métagénomique Type d'étude: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limites: Humans Langue: En Journal: Nat Med Sujet du journal: BIOLOGIA MOLECULAR / MEDICINA Année: 2019 Type de document: Article Pays d'affiliation: Italie